(R,S)-4-羟基环磷酰胺合成路线 （共 9 条）
反应条件
dimethylsulfide in methanol 0.0833333 h;
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 7 p. 1491 - 1496
反应条件
1: 27 percent / ozone, 30percent aq. H2O2 / acetone; H2O / Ambient temperature 2: Ph3P / CH2Cl2 / 0.25 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 4 p. 466 - 485
反应条件
triphenylphosphine in dichloromethane 0.25 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 4 p. 466 - 485
反应条件
2,6-dimethylpyridine T=37°C; apparent half-lives; various pH; Rate constant;
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 4 p. 466 - 485
反应条件
water in methanol T=37°C; var. buffers; effect of buffer conc. and comp. on the rate of reaction; Equilibrium constantMechanism;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 2 p. 427 - 431
反应条件
cacodylate buffer (pD 7.0) in water-d2 T=25°C; free energy differences; Equilibrium constant;
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 4 p. 490 - 494
反应条件
acetate bufer in water T=37°C; var. buffer conc., var. pH, var. ionic strength; Rate constantMechanism;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 2 p. 395 - 399
反应条件
lutidine buffer; sodium thiosulfate T=37°C; Product distribution;
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 4 p. 466 - 485
反应条件
2,6-dimethylpyridine T=37°C; apparent half-lives; various pH; Rate constant;
参考文献
Zon, Gerald; Ludeman, Susan Marie; Brandt, Joan A.; Boyd, Victoria L.; Oezkan, Gunay; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 4 p. 466 - 485
