对醛基苯甲酸合成路线

619-66-9对醛基苯甲酸+68-12-2N,N-二甲基甲酰胺→58287-76-6

参考文献

BIOMARIN PHARMACEUTICAL INC.; WANG, Bing; CHU, Daniel
Patent: WO2011/130661 A1, 2011 ;
Location in patent: Page/Page column 153 ;

619-66-9对醛基苯甲酸→58287-76-6

参考文献

American Cyanamid Company
Patent: US4289769 A1, 1981 ;

619-66-9对醛基苯甲酸+109-89-7二乙胺→58287-77-7N,N-二乙基苯甲酰胺-4-羧醛

参考文献

Zhang, Xiaoyan; Rice, Kenner C.; Calderon, Silvia N.; Kayakiri, Hiroshi; Smith, Larren; Coop, Andrew; Jacobson, Arthur E.; Rothman, Richard B.; Davis, Peg; Dersch, Christina M.; Porreca, Frank
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5455 - 5463

3282-30-2三甲基乙酰氯+619-66-9对醛基苯甲酸+109-89-7二乙胺+121-44-8三乙胺→58287-77-7N,N-二乙基苯甲酰胺-4-羧醛

参考文献

Chang, Kwen-Jen; Pendergast, William; Gengo, Peter J.
Patent: US2003/144299 A1, 2003 ;
US 20030144299 A1

619-66-9对醛基苯甲酸→58287-77-7N,N-二乙基苯甲酰胺-4-羧醛

参考文献

Chang, Kwen-Jen; Pendergast, William; Gengo, Peter J.
Patent: US2003/144299 A1, 2003 ;
US 20030144299 A1

619-66-9对醛基苯甲酸+109-89-7二乙胺+543-27-1氯甲酸异丁酯→58287-77-7N,N-二乙基苯甲酰胺-4-羧醛

参考文献

Brown, William; Walpole, Christopher; Plobeck, Niklas
Patent: US2003/119845 A1, 2003 ;

110-91-8吗啉+619-66-9对醛基苯甲酸→58287-80-24-(吗啉-4-羰基)苯甲醛

参考文献

Nitsche, Christoph; Steuer, Christian; Klein, Christian D.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 24 p. 7318 - 7337

619-66-9对醛基苯甲酸→604000-99-94-甲酰基-3-硝基苯甲酸(9ci)

参考文献

Takrouri, Khuloud; Chen, Ting; Papadopoulos, Evangelos; Sahoo, Rupam; Kabha, Eihab; Chen, Han; Cantel, Sonia; Wagner, Gerhard; Halperin, Jose A.; Aktas, Bertal H.; Chorev, Michael
European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 361 - 377

619-66-9对醛基苯甲酸→604000-99-94-甲酰基-3-硝基苯甲酸(9ci)

参考文献

SYNGENTA PARTICIPATIONS AG; CASSAYRE, Jérôme, Yves; RENOLD, Peter; PITTERNA, Thomas; EL QACEMI, Myriem
Patent: WO2013/26931 A1, 2013 ;
Location in patent: Page/Page column 153 ;

619-66-9对醛基苯甲酸+100-63-0苯肼→61471-39-4

参考文献

Kool, Eric T.; Park, Do-Hyoung; Crisalli, Pete
Journal of the American Chemical Society, 2013 , vol. 135, # 47 p. 17663 - 17666