2-溴-4'-甲基苯乙酮合成路线 （共 167 条）
反应条件
1: 2-[bis(benzylthio)methylene]-3-oxo-N-o-tolylbutanamide With sodium hydroxide in ethanol T=25°C; 0.833333 h; 2: α-bromo-4-methylacetophenone in ethanol T=25°C;
参考文献
Chinese Journal of Chemistry, , vol. 30, # 2 p. 367 - 371
反应条件
S4N4*SbCl5 in toluene 3 h; Heating;
参考文献
Kim, Kil-Joong; Kim, Kyongtae
Tetrahedron Letters, 1997 , vol. 38, # 24 p. 4227 - 4230
反应条件
1.1: hydroxylamine hydrochloride / water; methanol / 25 °C 2.1: sodium tetrahydroborate / water; acetonitrile / 0.17 h / 25 °C 3.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C 3.2: 18 h / 20 °C 4.1: C19H23BNO3(1-)*H(1+); borane-THF / 1,4-dioxane; tetrahydrofuran / 0 °C / |Inert atmosphere View Scheme
参考文献
Ou, Wenhua; Espinosa, Sandraliz; Melendez, Hector J.; Farre, Silvia M.; Alvarez, Jaime L.; Torres, Valerie; Martinez, Ileanne; Santiago, Kiara M.; Ortiz-Marciales, Margarita
Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5314 - 5327
反应条件
in ethanol 24 h; Heating;
参考文献
Klupsch, Frederique; Houssin, Raymond; Humbert, Luc; Imbenotte, Michel; Henichart, Jean-Pierre; Lhermitte, Michel
Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 9 p. 1318 - 1321
反应条件
Na2S*9H2O in water; acetone T=20°C; 1 h; Cooling with iceInert atmosphere;
参考文献
Su, Qiong; Zhao, Zi-Jian; Xu, Feng; Lou, Peng-Cai; Zhang, Kai; Xie, De-Xun; Shi, Lei; Cai, Qing-Yun; Peng, Zhi-Hong; An, De-Lie
European Journal of Organic Chemistry, 2013 , # 8 p. 1551 - 1557
反应条件
1: 1.) THF, RT, 1 h, 2.) THF, RT, 2 h 2: aq. NaOCl / CHCl3 / 0.5 h / Ambient temperature View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 90, # 1-4 p. 47 - 52
参考文献
European Journal of Organic Chemistry, , # 32 p. 6328 - 6334,7
反应条件
1: ethanol 2: NaBH4 / methanol View Scheme
参考文献
Corrodi,H. et al.
Journal of Medicinal Chemistry, 1963 , vol. 6, p. 751 - 755
反应条件
potassium hydrogensulfate in acetonitrile Reflux;
参考文献
Baghernejad, Bita; Heravi, Majid M.; Oskooie, Hossein A.
Synthetic Communications, 2011 , vol. 41, # 4 p. 589 - 593
反应条件
1: 2,2'-dinitrodiphenyl disulphide With samarium diiodide in tetrahydrofuran T=20°C; 0.5 h; 2: α-bromo-4-methylacetophenone in tetrahydrofuran T=20°C; 2 h;
参考文献
Zhong, Weihui; Chen, Xiaoyuan; Zhang, Yongmin
Heteroatom Chemistry, 2001 , vol. 12, # 3 p. 156 - 160
