2-氨基-4-硝基苯甲酸合成路线 （共 72 条）
反应条件
methoxylamine hydrochloride; potassium tert-butylate; copper diacetate in ethylene glycol dimethyl ether T=20°C; Substitution; Amination; 3 h;
参考文献
Seko, Shinzo; Miyake, Kunihito; Kavvamura, Norio
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 11 p. 1437 - 1444
反应条件
iron sulphate heptahydrate; ammonia in water T=50 - 60°C;
参考文献
Plater, M. John; Vassiliev, Ken
Journal of Chemical Research, 2011 , vol. 35, # 3 p. 129 - 132
反应条件
1: With copper(l) iodide; sodium azide; ethanol; caesium carbonate; N-methyl-2-(methylamino)ethylamine T=20 - 95°C; Inert atmosphereSealed tube; 2: With hydrogenchloride in water pH=2 - 3;
参考文献
Zhao, Haibo; Fu, Hua; Qiao, Renzhong
Journal of Organic Chemistry, 2010 , vol. 75, # 10 p. 3311 - 3316
反应条件
ethanol; sulfuric acid
参考文献
American Chemical Journal, , vol. 20, p. 222
反应条件
1: 77 percent / pyridine / titanium(IV) chloride / CCl4; tetrahydrofuran / 24 h 2: 75 percent / 1.) t-butyl alcohol, diethylamine, 2.) aq. sodium hydrogen carbonate / 1.) room temp., 48 h, 2.) chloroform View Scheme
参考文献
Synthesis, , # 8 p. 654 - 659
反应条件
1: potassium permanganate 2: alcohol; sulfuric acid View Scheme
参考文献
American Chemical Journal, , vol. 20, p. 222
反应条件
Streptomyces thioluteus para-aminobenzoate N-oxygenase
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 47 p. 8016 - 8018
反应条件
1: acetic acid / acetonitrile / 0.25 h 2: potassium permanganate / water / 1.5 h / 80 °C 3: hydrogenchloride / water / 1 h / |Reflux View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 51, # 1 p. 162 - 174
反应条件
diethylamine; tert-butyl alcohol 48 h; Ambient temperature;
参考文献
Kinastowski, Stefan; Wnuk, Stanislaw
Synthesis, 1983 , # 8 p. 654 - 659
反应条件
hydrogenchloride; potassium hydroxide; bromine 1.) heating, 1 h, 2.) 0 deg C; Yield given. Multistep reaction;
参考文献
Heterocycles, , vol. 35, # 2 p. 775 - 789
