3-甲基-1,2-苯并异噻唑合成路线 （共 18 条）
反应条件
1: NaOEt, urea / ethanol / Heating
2: aq. NaOH / ethanol / Heating
3: 165 °C
View Scheme
参考文献
Carrington,D.E.L. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 3006 - 3010
反应条件
1: NH2OH*HCl / aq. ethanol
2: polyphosphoric acid / 120 °C
View Scheme
参考文献
Clarke,K. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973 , p. 356 - 359
参考文献
Carrington,D.E.L. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 3006 - 3010
反应条件
in various solvent(s)
1 h; Heating; Further byproducts.;
参考文献
Leardini; McNab; Minozzi; Nanni
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1072 - 1078
反应条件
1: 60 percent / ethanol / 1.5 h / Heating
2: 45 percent / 0.5 h / 650 °C
View Scheme
参考文献
Creed; Leardini; McNab; Nanni; Nicolson; Reed
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1079 - 1085
反应条件
1: tetrahydrofuran / 1 h / 20 °C
2: tetrahydrofuran; light petroleum / 4 h / 0 - 5 °C
3: 18 percent / various solvent(s) / 1 h / Heating
View Scheme
参考文献
Leardini; McNab; Minozzi; Nanni
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1072 - 1078
反应条件
(i) 4-nitro benzoyl chloride, Et2O, (ii) HOCH2CH2OCH2CH2OH, (reflux); Multistep reaction;
参考文献
Carrington,D.E.L. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 3006 - 3010
参考文献
Bryce, Martin R.; Hanson, Peter; Vernon, John M.
Journal of the Chemical Society, Chemical Communications, 1982 , # 5 p. 299 - 300
