sodium hydroxide in methanol T=20°C; Hydrolysis; 2 h;

1: 93 percent / potassium carbonate / acetone; dimethylsulfoxide / 24 h / 20 °C 2: 53 percent / m-CPBA / CH2Cl2 / 0.75 h / 0 °C 3: 91 percent / 0.5 N aq. NaOH / methanol / 2 h / 20 °C View Scheme

1: 53 percent / m-CPBA / CH2Cl2 / 0.75 h / 0 °C 2: 91 percent / 0.5 N aq. NaOH / methanol / 2 h / 20 °C View Scheme

hydrogenchloride; bromine; acetic acid

2: hydrogen chloride; acetic acid; aqueous bromine View Scheme