1: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=20°C; 0.5 h; 2: With ammonia in 1,4-dioxane; N,N-dimethyl-formamide 2 h;

1: With borane-THF in tetrahydrofuran 24 h; 2: With water in tetrahydrofuran 3: With trifluoroacetic acid in water pH=3;