苯并[b]噻吩-3-醇 1,1-二氧化物合成路线 （共 9 条）
反应条件
1: diethyl ether 2: aq. NaOH solution View Scheme
参考文献
Arndt; Martius
Justus Liebigs Annalen der Chemie, 1932 , vol. 499, p. 228,283
反应条件
T=25°C; Rate constant;
参考文献
Pearson et al.
Journal of the American Chemical Society, 1955 , vol. 77, p. 527
反应条件
1: zinc chloride; hydrogen chloride 2: zinc; aq. NaOH solution View Scheme
参考文献
Mustafa; Zayed
Journal of the American Chemical Society, 1957 , vol. 79, p. 3500
反应条件
lithium diisopropyl amide in tetrahydrofuran
T=-80 - 20°C; 10 h;
参考文献
Cabiddu, M.Grazia; Cabiddu, Salvatore; Cadoni, Enzo; Demontis, Stefania; Fattuoni, Claudia; Melis, Stefana
Tetrahedron, 2002 , vol. 58, # 22 p. 4529 - 4533
参考文献
Weston; Suter
Journal of the American Chemical Society, 1939 , vol. 61, p. 389
反应条件
1: tetrachloromethane; chlorosulfuric acid / und anschliessenden Erhitzen auf 110grad
2: water
View Scheme
参考文献
Weston; Suter
Journal of the American Chemical Society, 1939 , vol. 61, p. 389
反应条件
1.1: TMEDA; BuLi / hexane / 1.25 h / 40 - 58 °C
1.2: 71 percent / hexane; diethyl ether / 2 h / -80 °C
2.1: 74 percent / 3-chloroperbenzoic acid / CH2Cl2 / 5 - 45 °C
3.1: 90 percent / LDA / tetrahydrofuran / 10 h / -80 - 20 °C
View Scheme
参考文献
Cabiddu, M.Grazia; Cabiddu, Salvatore; Cadoni, Enzo; Demontis, Stefania; Fattuoni, Claudia; Melis, Stefana
Tetrahedron, 2002 , vol. 58, # 22 p. 4529 - 4533
反应条件
1: 74 percent / 3-chloroperbenzoic acid / CH2Cl2 / 5 - 45 °C
2: 90 percent / LDA / tetrahydrofuran / 10 h / -80 - 20 °C
View Scheme
参考文献
Cabiddu, M.Grazia; Cabiddu, Salvatore; Cadoni, Enzo; Demontis, Stefania; Fattuoni, Claudia; Melis, Stefana
Tetrahedron, 2002 , vol. 58, # 22 p. 4529 - 4533
参考文献
McClelland; D'Silva
Journal of the Chemical Society, 1931 , p. 2972,2975
