4-甲基-7-乙酰氧基香豆素-β-D-吡喃半乳糖苷合成路线 （共 9 条）
反应条件
sodium methylate in methanol T=20°C; 0.5 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 4, # 24 p. 4453 - 4459
反应条件
1: 68 percent / TMSOTf / CH2Cl2 / 0.5 h / -78 °C 2: 83 percent / NaOMe / methanol / 0.5 h / 20 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 14 p. 2187 - 2193
反应条件
1: 1-methylimidazole / CH2Cl2 / 16 h / 20 °C 2: 68 percent / TMSOTf / CH2Cl2 / 0.5 h / -78 °C 3: 83 percent / NaOMe / methanol / 0.5 h / 20 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 14 p. 2187 - 2193
反应条件
1: 68 percent / TMSOTf / CH2Cl2 / 0.5 h / -78 °C 2: 83 percent / NaOMe / methanol / 0.5 h / 20 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 14 p. 2187 - 2193
反应条件
1.1: morpholine / dichloromethane / 20 °C / Inert atmosphere 2.1: dichloromethane / 1 h / 0 °C / Inert atmosphere 2.2: 0.5 h / 0 °C / Inert atmosphere 3.1: boron trifluoride dimethyl etherate / dichloromethane / 20 °C / Inert atmosphere 4.1: methanol; sodium methylate / 0.5 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 24 p. 8271 - 8277
反应条件
1: boron trifluoride dimethyl etherate / dichloromethane / 20 °C / Inert atmosphere 2: methanol; sodium methylate / 0.5 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 24 p. 8271 - 8277
反应条件
1: acetone; aq. NaOH solution 2: sodium methylate; methanol View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 24, p. 1099,1102
反应条件
magnesium chloride T=37°C; pH=7.5; 0.25 h; aq. phosphate bufferEnzymatic reaction; Kinetics; Concentration;
参考文献
Molecular Pharmacology, , vol. 79, # 3 p. 472 - 478
参考文献
Tamaru, Shun-Ichi; Kiyonaka, Shigeki; Hamachi, Itaru
Chemistry - A European Journal, 2005 , vol. 11, # 24 p. 7294 - 7304
