4-苯甲酰基-苯甲酸甲酯合成路线 （共 24 条）
反应条件
(3aS,7aS)-1,3-di-o-tolyl-octahydro-benzoimidazole-2-thione; potassium carbonate; PdI2 in methoxybenzene
T=80°C; Suzuki reaction; 10 h;
参考文献
Mingji, Dai; Liang, Bo; Wang, Cuihua; You, Zejin; Xiang, Jing; Dong, Guangbin; Chen, Jiahua; Yang, Zhen
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1669 - 1673
反应条件
Friedel-Crafts acylation;
参考文献
Nishitani, Shinji; Bodor, Nicholas
Revue Roumaine de Chimie, 1991 , vol. 36, # 4-7 p. 635 - 646
反应条件
potassium fluoride; bis(η3-allyl-μ-chloropalladium(II)) in various solvent(s)
T=100°C; P=760 Torr; 5 h;
参考文献
Hatanaka, Yasuo; Fukushima, Satoshi; Hiyama, Tamejiro
Tetrahedron, 1992 , vol. 48, # 11 p. 2113 - 2126
反应条件
1: terephthalic acid monomethyl ester With N,N'-disuccinimidyl-carbonate; sodium carbonate; tri-cyclo-hexyl-phosphine; Pd(F6-acac)2 in tetrahydrofuran
T=60°C;
2: 3,4,5-trimethoxyphenylboronic acid in tetrahydrofuran
T=60°C; 20 h; Further stages.;
参考文献
Goossen; Ghosh
Chemical Communications, 2001 , # 20 p. 2084 - 2085
反应条件
Li(acac) in 1-methyl-pyrrolidin-2-one; diethyl ether
T=50°C; 5 h;
参考文献
Kneisel, Florian F.; Dochnahl, Maximilian; Knochel, Paul
Angewandte Chemie - International Edition, 2004 , vol. 43, # 8 p. 1017 - 1021
反应条件
thionyl chloride
7 h; Heating / reflux;
参考文献
Smithkline Beecham Corporation
Patent: US2008/167360 A1, 2008 ;
Location in patent: Page/Page column 22 ;
US 20080167360 A1
反应条件
palladium diacetate; triphenylphosphine in 1,4-dioxane
T=50°C; 10 h;
参考文献
Tatamidani, Hiroto; Kakiuchi, Fumitoshi; Chatani, Naoto
Organic Letters, 2004 , vol. 6, # 20 p. 3597 - 3599
反应条件
Cl2Ni(1,2-bis(diphenylphosphino)ethane); water; zinc(II) chloride in 1,4-dioxane
T=80°C; 8 h; Inert atmosphere;
参考文献
Wong, Ying-Chieh; Parthasarathy, Kanniyappan; Cheng, Chien-Hong
Organic Letters, 2010 , vol. 12, # 8 p. 1736 - 1739
反应条件
bis(acetylacetonato) palladium; N-ethyl-N,N-diisopropylamine; bis(dibenzylideneacetone)-palladium(0); [(t-Bu)3PH]BF4; cataCXium® AHI in toluene
T=80°C; Suzuki-Miyaura Coupling; 16 h; Inert atmosphere;
参考文献
Bjerglund, Klaus M.; Skrydstrup, Troels; Molander, Gary A.
Organic Letters, 2014 , vol. 16, # 7 p. 1888 - 1891
反应条件
3,4,7,8-tetra-methyl-1,10-phenanthroline; oxygen; caesium carbonate; cobalt(II) chloride in toluene; acetonitrile
T=80°C; 12 h;
参考文献
Karthikeyan, Jaganathan; Parthasarathy, Kanniyappan; Cheng, Chien-Hong
Chemical Communications, 2011 , vol. 47, # 37 p. 10461 - 10463
