2,5-二溴-4-硝基-1H-咪唑合成路线 (共 3 条)
反应条件
iso-butyronitrile; sodium iodide T=20 - 105°C; Inert atmosphere;
参考文献
SHIKOKU CHEMICALS CORPORATION
Patent: EP2141151 A1, 2010 ;
Location in patent: Page/Page column 8 ;
反应条件
in tetrahydrofuran T=20°C; Methylation; 1 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 37, # 1 p. 119 - 126
反应条件
in diethyl ether T=20°C; 1 h;
参考文献
Chauviere, Gerard; Bouteille, Bernard; Enanga, Bertin; De Albuquerque, Cristina; Croft, Simon L.; Dumas, Michel; Perie, Jacques
Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 427 - 440