1: With zinc(II) chloride in 1,2-dichloro-ethane Heating / reflux; 2: With hydrogenchloride; water in 1,2-dichloro-ethane T=90°C; 4 h; Product distribution / selectivity;
参考文献
LG LIFE SCIENCES LTD.
Patent: WO2007/64077 A1, 2007 ;
Location in patent: Page/Page column 7 ;
1: 5-fluoro-2,6-dihydroxynicotinonitrile With phosphorus pentachloride; trichlorophosphate Heating / reflux; 2: malonic acid ethyl ester monopotassium salt With zinc(II) chloride in 1,2-dichloro-ethane Heating / reflux; 3: With hydrogenchloride; water in 1,2-dichloro-ethane T=90°C; 4 h; Product distribution / selectivity;
参考文献
LG LIFE SCIENCES LTD.
Patent: WO2007/64077 A1, 2007 ;
Location in patent: Page/Page column 6 ;