乙基2,4-二甲基-3-糠酸酯合成路线 （共 20 条）
反应条件
sodium hydroxide Hydrolysis; 2 h; Heating;
参考文献
Wenkert, Ernest; Khatuya, Haripada; Klein, Phillip S.
Tetrahedron Letters, 1999 , vol. 40, # 28 p. 5171 - 5174
反应条件
Pt(PPh3)2(C2H4) in tetrahydrofuran
T=80°C; Substitution; cyclization, isomerization; 2 h;
参考文献
Kadota, Joji; Komori, Shinji; Fukumoto, Yoshiya; Murai, Shinji
Journal of Organic Chemistry, 1999 , vol. 64, # 20 p. 7523 - 7527
反应条件
potassium carbonate in dimethyl sulfoxide
T=120°C; 6 h;
参考文献
Akhmedov, Sh. T.; Sadykhov, N. S.; Ismailov, V. M.; Akhundova, M. A.; Sadovaya, N. K.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 12 p. 1291 - 1295
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 12 p. 1602 - 1606
反应条件
potassium carbonate in dimethyl sulfoxide
Heating;
参考文献
Akhmedov, Sh. T.; Sadykhov, N. S.; Ismailov, V. M.; Sadovaya, N. K.; Karimov, F. N.; Zefirov, N. S.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 10 p. 1184
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 10 p. 1428 - 1429
反应条件
hydrogenchloride; triethylamine in diethyl ether
T=-5 - 0°C; Condensation; 64 h;
参考文献
Wenkert, Ernest; Khatuya, Haripada; Klein, Phillip S.
Tetrahedron Letters, 1999 , vol. 40, # 28 p. 5171 - 5174
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane
Ambient temperature;
参考文献
Chan, Wing Hong; Lee, Albert W. M.; Chan, Eddy T. T.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 8 p. 945 - 946
反应条件
1.1: sodium hydride / mineral oil; dimethyl sulfoxide / |Inert atmosphere
1.2: 1.5 h / 20 °C / |Inert atmosphere
2.1: manganese(IV) oxide / chlorobenzene / 8 h / 130 °C / |Microwave irradiation
View Scheme
参考文献
Chagarovsky, Alexey O.; Budynina, Ekaterina M.; Ivanova, Olga A.; Villemson, Elena V.; Rybakov, Victor B.; Trushkov, Igor V.; Melnikov, Mikhail Ya.
Organic Letters, 2014 , vol. 16, # 11 p. 2830 - 2833
反应条件
in acetic acid; N,N-dimethyl-formamide
T=60°C; 8 h; Green chemistry;
参考文献
Cao, Hua; Jiang, Huan-Feng; Zhou, Xiao-Song; Qi, Chao-Rong; Lin, Yuan-Guang; Wu, Jian-Yong; Liang, Qi-Mei
Green Chemistry, 2012 , vol. 14, # 10 p. 2710 - 2714
反应条件
1: Ag2CO3, celite / acetonitrile
2: NaIO4 / methanol; H2O / 24 h / Ambient temperature
3: pyridine, Al2O3 / CCl4 / 2 h / Heating
View Scheme
参考文献
Lee Yong Rok, R.; Kim, Nam Suk; Kim, Byung So
Tetrahedron Letters, 1997 , vol. 38, # 32 p. 5671 - 5674
反应条件
1: 84 percent / N-bromo succinimide / CH2Cl2 / 2 h / 10 °C
2: 1) n-Bu3SnH, azobisisobutyronitrile, 2) toluene-p-sulfonic acid / 1) benzene, 80 deg C, 1.5 h, 2) benzene, room temp., 15 min
View Scheme
参考文献
Srikrishna, A.; Krishnan, K.
Tetrahedron Letters, 1988 , vol. 29, # 39 p. 4995 - 4996
