2,2-二甲基-4-氰基丁醛合成路线 （共 23 条）
反应条件
sulfuric acid; nitric acid
参考文献
Bailey,A.S. et al.
Canadian Journal of Chemistry, 1961 , vol. 39, p. 1147 - 1152
反应条件
1: With hydrogen; acetic acid in ethanol T=20°C; 18 h; 2: With sodium hydroxide in tert-butyl methyl ether; water
参考文献
Organic Process Research and Development, , vol. 15, # 1 p. 112 - 122
反应条件
1: tetrahydrofuran; lithium-<tri-tert-butoxyalanate> 3: sodium tert-pentylate 4: KOH; ethylene glycol View Scheme
参考文献
Julia; Rouault
Bulletin de la Societe Chimique de France, 1959 , p. 1833,1839
反应条件
1: 195 - 200 °C 2: aq. NaOH / ethanol 3: aq. HCl 4: LiAlH4 / diethyl ether View Scheme
参考文献
Ketcham,R.; Mah,S.
Journal of Medicinal Chemistry, 1971 , vol. 14, p. 743 - 747
反应条件
1: KMnO4 2: (electrolysis) View Scheme
参考文献
Cauquis,G.; Haemmerle,B.
Bulletin de la Societe Chimique de France, 1970 , p. 190 - 192
参考文献
Ketcham,R.; Mah,S.
Journal of Medicinal Chemistry, 1971 , vol. 14, p. 743 - 747
反应条件
1: 195 - 200 °C 2: benzene; diethyl ether View Scheme
参考文献
Ketcham,R.; Mah,S.
Journal of Medicinal Chemistry, 1971 , vol. 14, p. 743 - 747
反应条件
1: tetrahydrofuran; lithium-<tri-tert-butoxyalanate> 2: aqueous KOH-solution / Ansaeuern und Destillieren View Scheme
参考文献
Julia; Rouault
Bulletin de la Societe Chimique de France, 1959 , p. 1833,1839
参考文献
Feichtinger,H. et al.
Chemische Berichte, 1978 , vol. 111, p. 1721 - 1732
反应条件
potassium permanganate
参考文献
Cauquis,G.; Haemmerle,B.
Bulletin de la Societe Chimique de France, 1970 , p. 190 - 192
