2-(4-溴苯基)-1H-吲哚合成路线 （共 27 条）
反应条件
potassium carbonate; L-proline; copper(I) bromide in dimethyl sulfoxide
T=100°C; 3 h; Inert atmosphere;
参考文献
Ponpandian, Thanasekaran; Muthusubramanian, Shanmugam
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4248 - 4252
反应条件
2,6-di-tert-butyl-pyridine; copper(II) bis(trifluoromethanesulfonate) in dichloromethane
T=35°C; 48 h;
参考文献
Phipps, Robert J.; Grimster, Neil P.; Gaunt, Matthew J.
Journal of the American Chemical Society, 2008 , vol. 130, # 26 p. 8172 - 8174
反应条件
1: With acetic acid in methanol
T=80°C; 0.166667 h; Inert atmosphereMicrowave irradiation;
2: With potassium tert-butylate in tetrahydrofuran
T=25°C; 1 h; Inert atmosphere;
参考文献
Kraus, George A.; Guo, Haitao
Organic Letters, 2008 , vol. 10, # 14 p. 3061 - 3063
反应条件
(1,3-di(2,4,6-(CH3)3-C6H2)-imidazol-2-ylidene)Pd(OAc)2; acetic acid
T=80°C; 15 h;
参考文献
Deprez, Nicholas R.; Kalyani, Dipannita; Krause, Andrew; Sanford, Melanie S.
Journal of the American Chemical Society, 2006 , vol. 128, # 15 p. 4972 - 4973
反应条件
sulfuric acid; silver(I) acetate; palladium dichloride in N,N-dimethyl-formamide; acetonitrile
T=100°C; 0.666667 h; Sealed tubeMicrowave irradiation; regioselective reaction;
参考文献
Miao, Tao; Li, Pinhua; Wang, Guan-Wu; Wang, Lei
Chemistry - An Asian Journal, 2013 , vol. 8, # 12 p. 3185 - 3190
反应条件
potassium tert-butylate; palladium diacetate; triphenylphosphine in dimethyl sulfoxide
T=20 - 120°C; intramolecular Heck reaction; Inert atmosphere;
参考文献
Mao, Hui; Wan, Jie-Ping; Pan, Yuanjiang; Sun, Cuirong
Tetrahedron Letters, 2010 , vol. 51, # 14 p. 1844 - 1846
反应条件
1: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in N,N-dimethyl acetamide
T=20°C; Sonogashira Cross-Coupling; 1 h;
2: With sodium hydroxide in N,N-dimethyl-aniline
T=140°C;
参考文献
Yu, Xufen; Park, Eun-Jung; Kondratyuk, Tamara P.; Pezzuto, John M.; Sun, Dianqing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 44 p. 8835 - 8847
反应条件
sodium hydroxide in dimethyl sulfoxide
T=20 - 25°C; 0.5 h;
参考文献
Wojciechowski, Krzysztof; Makosa, Mieczyslaw
Bulletin des Societes Chimiques Belges, 1986 , vol. 95, # 8 p. 671 - 674
反应条件
PPA
T=70 - 80°C; 0.5 h;
参考文献
Chikvaidze, I. Sh.; Mumladze, E. A.; Samsoniya, Sh. A.; Suvorov, N. N.
Pharmaceutical Chemistry Journal, 1994 , vol. 28, # 10 p. 751 - 755
Khimiko-Farmatsevticheskii Zhurnal, 1994 , vol. 28, # 10 p. 47 - 50
反应条件
potassium acetate; palladium diacetate; bis(1,1-diphenylphosphino)methane in water
T=110°C; 24 h; regioselective reaction;
参考文献
Joucla, Lionel; Batail, Nelly; Djakovitch, Laurent
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 17 p. 2929 - 2936
