4-(反-4-丙基环己基)苯腈合成路线 （共 17 条）
反应条件
1: AlCl3 / 45 °C 2: hydrazine hydrate / bis-(2-hydroxy-ethyl) ether / or in 1:1 mixture of triethanolamine and glycerol 3: AlCl3 / 1,2-dichloro-ethane / 0.5 h 4: aq. NaOH, Br2 / dioxane / 3 h / 35 - 40 °C 5: SOCl2 / 1 h / Heating 6: 25percent aq. NH4OH 7: 56 percent / SOCl2, dimethylformamide / 1.5 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, , vol. 19, # 8 p. 1669 - 1674
反应条件
thionyl chloride; N,N-dimethyl-formamide 1.5 h; Ambient temperature;
参考文献
Bezborodov, V. S.; Bubel', O. N.; Konovalov, V. A.; Ptashnikov, Yu. L.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 8 p. 1669 - 1674
反应条件
1: AlCl3 / 45 °C 2: hydrazine hydrate / bis-(2-hydroxy-ethyl) ether / or in 1:1 mixture of triethanolamine and glycerol 3: AlCl3 / 1,2-dichloro-ethane / 0.5 h 4: aq. NaOH, Br2 / dioxane / 3 h / 35 - 40 °C 5: SOCl2 / 1 h / Heating 6: 25percent aq. NH4OH 7: 56 percent / SOCl2, dimethylformamide / 1.5 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, , vol. 19, # 8 p. 1669 - 1674
反应条件
1: AlCl3 / 45 °C 2: hydrazine hydrate / bis-(2-hydroxy-ethyl) ether / or in 1:1 mixture of triethanolamine and glycerol 3: AlCl3 / 1,2-dichloro-ethane / 0.5 h 4: aq. NaOH, Br2 / dioxane / 3 h / 35 - 40 °C 5: SOCl2 / 1 h / Heating 6: 25percent aq. NH4OH 7: 56 percent / SOCl2, dimethylformamide / 1.5 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, , vol. 19, # 8 p. 1669 - 1674
反应条件
1: 2.) 10percent aq. HCl / 1.) diethyl ether, 1 h, heating 2: p-toluenesulfonic acid / toluene / Heating 3: H2 / 10percent Pd/C / ethanol 4: AlCl3 / 1,2-dichloro-ethane / 0.5 h 5: aq. NaOH, Br2 / dioxane / 3 h / 35 - 40 °C 6: SOCl2 / 1 h / Heating 7: 25percent aq. NH4OH 8: 56 percent / SOCl2, dimethylformamide / 1.5 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, , vol. 19, # 8 p. 1669 - 1674
反应条件
1: H2 / 10percent Pd/C / ethanol 2: AlCl3 / 1,2-dichloro-ethane / 0.5 h 3: aq. NaOH, Br2 / dioxane / 3 h / 35 - 40 °C 4: SOCl2 / 1 h / Heating 5: 25percent aq. NH4OH 6: 56 percent / SOCl2, dimethylformamide / 1.5 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, , vol. 19, # 8 p. 1669 - 1674
反应条件
1: H2 / 10percent Pd/C / ethanol 2: AlCl3 / 1,2-dichloro-ethane / 0.5 h 3: aq. NaOH, Br2 / dioxane / 3 h / 35 - 40 °C 4: SOCl2 / 1 h / Heating 5: 25percent aq. NH4OH 6: 56 percent / SOCl2, dimethylformamide / 1.5 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, , vol. 19, # 8 p. 1669 - 1674
反应条件
1: p-toluenesulfonic acid / toluene / Heating 2: H2 / 10percent Pd/C / ethanol 3: AlCl3 / 1,2-dichloro-ethane / 0.5 h 4: aq. NaOH, Br2 / dioxane / 3 h / 35 - 40 °C 5: SOCl2 / 1 h / Heating 6: 25percent aq. NH4OH 7: 56 percent / SOCl2, dimethylformamide / 1.5 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, , vol. 19, # 8 p. 1669 - 1674
反应条件
1: p-toluenesulfonic acid / toluene / Heating 2: H2 / 10percent Pd/C / ethanol 3: AlCl3 / 1,2-dichloro-ethane / 0.5 h 4: aq. NaOH, Br2 / dioxane / 3 h / 35 - 40 °C 5: SOCl2 / 1 h / Heating 6: 25percent aq. NH4OH 7: 56 percent / SOCl2, dimethylformamide / 1.5 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, , vol. 19, # 8 p. 1669 - 1674
反应条件
1: NaBH4 / propan-1-ol / 4 h / 30 - 35 °C 2: p-toluenesulfonic acid / toluene / Heating 3: H2 / 10percent Pd/C / ethanol 4: AlCl3 / 1,2-dichloro-ethane / 0.5 h 5: aq. NaOH, Br2 / dioxane / 3 h / 35 - 40 °C 6: SOCl2 / 1 h / Heating 7: 25percent aq. NH4OH 8: 56 percent / SOCl2, dimethylformamide / 1.5 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 19, p. 1479 - 1483
Zhurnal Organicheskoi Khimii, , vol. 19, # 8 p. 1669 - 1674
