2-甲基-1-苯基-1-丙醇合成路线 （共 136 条）
反应条件
LaCl(O-i-Pr)2 in tetrahydrofuran T=60°C; 2 h;
参考文献
Harrad, Mohamed Anouar; Boualy, Brahim; El Firdoussi, Larbi; Mehdi, Ahmad; Santi, Claudio; Giovagnoli, Stefano; Nocchetti, Morena; Ait Ali, Mustapha
Catalysis Communications, 2013 , vol. 32, p. 92 - 100
反应条件
n-butyllithium in diethyl ether T=0 - 20°C; 12 h;
参考文献
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA; HOYE, Adam, T.; KIM, Won-suk; MARTINEZ-SOLORIO, Dionicio; SMITH, Amos, B.; SANCHEZ, Luis; TONG, Rongbiao; NGUYEN, Minh, Huu
Patent: WO2013/185021 A2, 2013 ;
Location in patent: Page/Page column 37 ;
反应条件
chromium dichloride; lithium iodide; B12 in N,N-dimethyl-formamide T=20°C; Takai-Utimoto reaction; 16 h;
参考文献
Wessjohann, Ludger A.; Schmidt, Gisela; Schrekker, Henri S.
Synlett, 2007 , # 13 p. 2139 - 2141
反应条件
methanol; 1,3-disulfonic acid imidazolium hydrogen sulfate T=20°C; 0.1 h; Green chemistry;
参考文献
Shirini, Farhad; Khaligh, Nader Ghaffari; Akbari-Dadamahaleh, Somayeh
Journal of Molecular Catalysis A: Chemical, 2012 , vol. 365, p. 15 - 23
反应条件
1: bromobenzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2: isobutyraldehyde in tetrahydrofuran; hexane T=-78 - 20°C; Further stages.;
参考文献
Driver, Tom G.; Harris, Jason R.; Woerpel
Journal of the American Chemical Society, 2007 , vol. 129, # 13 p. 3836 - 3837
反应条件
1: 2-monochloropropane With zinc(II) chloride in tetrahydrofuran T=20°C; 1 h; 2: 1-phenyl-2-methyl-1-propanone in tetrahydrofuran T=0°C; 2 h;
参考文献
Journal of the American Chemical Society, , vol. 128, # 31 p. 9998 - 9999
反应条件
1: 2-monochloropropane With zinc(II) chloride in tetrahydrofuran T=20°C; 1 h; 2: benzoic acid ethyl ester in tetrahydrofuran T=0°C; 2 h;
参考文献
Journal of the American Chemical Society, , vol. 128, # 31 p. 9998 - 9999
反应条件
1: 1-benzyl-tetrahydro-thiophenium tetrafluoroborate With lithium hexamethyldisilazane in tetrahydrofuran; dichloromethane T=-78°C; 1 h; 2: B-iPr-9-BBN in tetrahydrofuran; dichloromethane T=-100 - 0°C; 3: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran; dichloromethane T=0 - 20°C; Further stages.;
参考文献
Fang, Guang Y.; Wallner, Olov A.; Di Blasio, Nadia; Ginesta, Xavier; Harvey, Jeremy N.; Aggarwal, Varinder K.
Journal of the American Chemical Society, 2007 , vol. 129, # 47 p. 14632 - 14639
反应条件
1: isopropylmagnesium chloride With sodium methylate; zinc(II) chloride in diethyl ether T=0 - 20°C; Inert atmosphere; 2: benzaldehyde With (S)-N-(3-methyl-1-(1-pyrrolidin-1-yl)butan-2-yl) diphenylphosphinic amideamine in diethyl ether T=20°C; Inert atmosphere;
参考文献
Hatano, Manabu; Mizuno, Tomokazu; Ishihara, Kazuaki
Chemical Communications, 2010 , vol. 46, # 30 p. 5443 - 5445
反应条件
1: isopropyl bromide With iodine; magnesium in diethyl ether 0.5 h; Heating; 2: benzaldehyde in diethyl ether 2 h;
参考文献
Patel, Sabita; Panda, Mamata P.; Kuanar, Minati; Mishra
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 6 p. 1299 - 1301
