反应条件
1.1: triphenylphosphine; di-isopropyl azodicarboxylate / ethylene glycol dimethyl ether / 2.17 h / 25 - 30 °C / |Inert atmosphere; |Large scale
1.2: 10 h / -15 - 22 °C / |Inert atmosphere; |Large scale
2.1: sodium carbonate / methanol; dichloromethane / 0.75 h / 25 °C / pH 10 / |Darkness; |Inert atmosphere; |Large scale
2.2: 2.25 h / 30 °C / |Darkness; |Inert atmosphere; |Large scale
View Scheme
参考文献
Busacca, Carl A.; Cerreta, Mike; Dong, Yong; Eriksson, Magnus C.; Farina, Vittorio; Feng, XuWu; Kim, Ji-Young; Lorenz, Jon C.; Sarvestani, Max; Simpson, Robert; Varsolona, Rieh; Vitous, Jana; Campbell, Scot J.; Davis, Mark S.; Jones, Paul-James; Norwood, Daniel; Qiu, Fenghe; Beaulieu, Pierre L.; Duceppe, Jean-Simon; Hache, Bruno; Brong, Jim; Chiu, Fang-Ting; Curtis, Tom; Kelley, Jason; Lo, Young S.; Powner, Tory H.
Organic Process Research and Development, 2008 , vol. 12, # 4 p. 603 - 613