TYR-D-ALA-GLY-PHE-MET-NH2合成路线 (共 12 条)
反应条件
carboxypeptidase W in water T=30°C; Kinetics;
参考文献
Umetsu, Hironori; Hishinuma, Kiyoshi; Wake, Hitoshi; Takeuchi, Michio; Ichishima, Eiji
Phytochemistry, 1997 , vol. 45, # 5 p. 907 - 910
反应条件
carboxypeptidase W in water T=30°C; Kinetics;
参考文献
Umetsu, Hironori; Hishinuma, Kiyoshi; Wake, Hitoshi; Takeuchi, Michio; Ichishima, Eiji
Phytochemistry, 1997 , vol. 45, # 5 p. 907 - 910
反应条件
carboxypeptidase W in water T=30°C; Kinetics;
参考文献
Umetsu, Hironori; Hishinuma, Kiyoshi; Wake, Hitoshi; Takeuchi, Michio; Ichishima, Eiji
Phytochemistry, 1997 , vol. 45, # 5 p. 907 - 910
反应条件
hydrogenchloride; acetic acid in various solvent(s)
1.5 h;
参考文献
Audigier; Mazarguil; Gout; Cros
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
反应条件
1: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / formamide / 10 h. 0 deg C, 10 h. room temp.
2: H2O, NaOH / methanol
3: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide
4: H2O, NaOH / methanol
5: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide
6: NH3 / methanol
7: HCl, acetic acid / various solvent(s) / 1.5 h
View Scheme
参考文献
Audigier; Mazarguil; Gout; Cros
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
反应条件
1: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide
2: H2O, NaOH / methanol
3: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide
4: NH3 / methanol
5: HCl, acetic acid / various solvent(s) / 1.5 h
View Scheme
参考文献
Audigier; Mazarguil; Gout; Cros
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
反应条件
1: H2O, NaOH / methanol
2: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / formamide / 10 h. 0 deg C, 10 h. room temp.
3: H2O, NaOH / methanol
4: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide
5: H2O, NaOH / methanol
6: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide
7: NH3 / methanol
8: HCl, acetic acid / various solvent(s) / 1.5 h
View Scheme
参考文献
Audigier; Mazarguil; Gout; Cros
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
反应条件
1: H2O, NaOH / methanol
2: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide
3: H2O, NaOH / methanol
4: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide
5: NH3 / methanol
6: HCl, acetic acid / various solvent(s) / 1.5 h
View Scheme
参考文献
Audigier; Mazarguil; Gout; Cros
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
反应条件
1: NH3 / methanol
2: HCl, acetic acid / various solvent(s) / 1.5 h
View Scheme
参考文献
Audigier; Mazarguil; Gout; Cros
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177
反应条件
1: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide
2: NH3 / methanol
3: HCl, acetic acid / various solvent(s) / 1.5 h
View Scheme
参考文献
Audigier; Mazarguil; Gout; Cros
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 173 - 177