2,3-二氢-4-氨基苯并呋喃合成路线 （共 5 条）
反应条件
1: With hydrogen bromide in water T=100°C; 2: With sodium hydroxide in water pH=9;
参考文献
MEMORY PHARMACEUTICALS CORPORATION
Patent: US2008/200471 A1, 2008 ;
Location in patent: Page/Page column 60; 61-62 ;
US 20080200471 A1
反应条件
1: With hydrogen bromide in water; acetic acid T=20°C; 4 h; Heating / reflux; 2: With sodium hydroxide in water; acetic acid pH=14;
参考文献
VERNALIS RESEARCH LIMITED
Patent: US2005/187282 A1, 2005 ;
Location in patent: Page/Page column 9-10 ;
US 20050187282 A1
反应条件
hydrogenchloride; water in methanol 48 h; Heating / reflux;
参考文献
WO2004/103996 A1, ;
Page 52 ;
WO 2004/103996 A1
反应条件
rhodium in ethanol; hydrogen
反应条件
N-chloro-succinimide in benzene
2 h; Heating; Yield given;
参考文献
Marburg, S.; Tolman, R. L.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 9 p. 1333 - 1335
