dihydrogen peroxide; ammonium chloride in dichloromethane; water T=3 - 20°C; 1 h;

1: With lithium hexamethyldisilazane in tetrahydrofuran; hexane T=-78°C; 0.666667 h; 2: With chloro-trimethyl-silane in tetrahydrofuran; hexane T=-78 - 20°C; 0.583333 h; 3: With 4-methoxypyridine-N-oxide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in dimethyl sulfoxide

tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 1,2-bis-(diphenylphosphino)ethane in tetrahydrofuran T=65°C; 1 h;

water; pyridinium p-toluenesulfonate in acetone 24 h; Heating; Title compound not separated from byproducts;

manganese triacetate in benzene 8 h; Heating;

pyridinium p-toluenesulfonate in water; acetone Heating; Yield given. Title compound not separated from byproducts;

1: 91 percent / 5percent sulfuric acid / 5 h / Heating 2: 92 percent / 2,2-dimethoxypropane, p-toluenesulfonic acid / benzene / 6 h / Heating 3: p-toluenesulfonic acid / benzene / 4 h / Heating 4: sodium periodate / H2O; methanol / 10 h / 60 °C 5: 73 percent / potassium tert-butoxide / CCl4; 2-methyl-propan-2-ol / 20 h / 50 - 55 °C 6: pyridinium p-toluenesulfonate, water / acetone / 24 h / Heating View Scheme

1.1: potassium carbonate / acetone / 5 h / Reflux 1.2: 40 h / Reflux 2.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -70 - -55 °C / Inert atmosphere 2.2: 0.5 h / -70 - 0 °C 3.1: dihydrogen peroxide; ammonium chloride / dichloromethane; water / 1 h / 3 - 20 °C View Scheme

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / 0 - 20 °C 1.2: 0 - 20 °C 2.1: triphenylphosphine; palladium diacetate / tetrahydrofuran / 0.75 h / 65 °C 3.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -70 - -55 °C / Inert atmosphere 3.2: 0.5 h / -70 - 0 °C 4.1: dihydrogen peroxide; ammonium chloride / dichloromethane; water / 1 h / 3 - 20 °C View Scheme

1.1: triphenylphosphine; palladium diacetate / tetrahydrofuran / 0.75 h / 65 °C 2.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -70 - -55 °C / Inert atmosphere 2.2: 0.5 h / -70 - 0 °C 3.1: dihydrogen peroxide; ammonium chloride / dichloromethane; water / 1 h / 3 - 20 °C View Scheme