609806-82-8合成路线

参考文献

Boehringer Ingelheim Pharmaceuticals, Inc.
Patent: WO2003/104195 A1, 2003 ;
Location in patent: Page 63 ;
WO 03/104195 A1

851314-92-6+

104863-67-4N-甲氧基-N-甲基-2,2,2-三氟乙酰胺

609806-82-8

参考文献

Boehringer Ingelheim Pharmaceuticals, Inc.
Patent: US2005/209488 A1, 2005 ;
Location in patent: Page/Page column 7-8 ;
US 20050209488 A1

400-31-71,1,1-三氟-4-甲基-3-戊烯-2-酮+

188132-02-75-氟-2-甲氧苯基溴化镁

609806-82-8

参考文献

Riether, Doris; Harcken, Christian; Razavi, Hossein; Kuzmich, Daniel; Gilmore, Thomas; Bentzien, Joerg; Pack, Edward J.; Souza, Donald; Nelson, Richard M.; Kukulka, Alison; Fadra, Tazmeen N.; Zuvela-Jelaska, Ljiljana; Pelletier, Josephine; Dinallo, Roger; Panzenbeck, Mark; Torcellini, Carol; Nabozny, Gerald H.; Thomson, David S.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 18 p. 6681 - 6698

217195-91-02-羟基-2-(三氟甲基)-4-甲基-4-戊酸乙酯

609806-82-8

参考文献

Kuzmich, Daniel; Kirrane, Tom; Proudfoot, John; Bekkali, Younes; Zindell, Renee; Beck, Laura; Nelson, Richard; Shih, Cheng-Kon; Kukulka, Alison J.; Paw, Zofia; Reilly, Patty; Deleon, Rodney; Cardozo, Mario; Nabozny, Gerald; Thomson, David
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 18 p. 5025 - 5031

217195-92-1

609806-82-8

参考文献

Kuzmich, Daniel; Kirrane, Tom; Proudfoot, John; Bekkali, Younes; Zindell, Renee; Beck, Laura; Nelson, Richard; Shih, Cheng-Kon; Kukulka, Alison J.; Paw, Zofia; Reilly, Patty; Deleon, Rodney; Cardozo, Mario; Nabozny, Gerald; Thomson, David
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 18 p. 5025 - 5031

459-60-94-氟苯甲醚

609806-82-8

参考文献

Kuzmich, Daniel; Kirrane, Tom; Proudfoot, John; Bekkali, Younes; Zindell, Renee; Beck, Laura; Nelson, Richard; Shih, Cheng-Kon; Kukulka, Alison J.; Paw, Zofia; Reilly, Patty; Deleon, Rodney; Cardozo, Mario; Nabozny, Gerald; Thomson, David
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 18 p. 5025 - 5031

609806-82-8

566920-38-5

参考文献

Razavi, Hossein; Riether, Doris; Harcken, Christian; Bentzien, Joerg; Dinallo, Roger M.; Souza, Donald; Nelson, Richard M.; Kukulka, Alison; Fadra-Khan, Tazmeen N.; Pack Jr., Edward J.; Zuvela-Jelaska, Ljiljana; Pelletier, Josephine; Panzenbeck, Mark; Torcellini, Carol A.; Proudfoot, John R.; Nabozny, Gerald H.; Thomson, David S.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 8 p. 1934 - 1940