N-(4-戊炔基)酞酰亚胺合成路线 （共 13 条）
反应条件
in N,N-dimethyl-formamide Gabriel Amine Synthesis;
参考文献
Pigza, Julie A.; Han, Jeong-Seok; Chandra, Aroop; Mutnick, Daniel; Pink, Maren; Johnston, Jeffrey N.
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 822 - 843
反应条件
Mitsunobu conditions;
参考文献
Tiecco, Marcello; Testaferri, Lorenzo; Temperini, Andrea; Bagnoli, Luana; Marini, Francesca; Santi, Claudio; Terlizzi, Raffaella
European Journal of Organic Chemistry, 2004 , # 16 p. 3447 - 3458
反应条件
potassium iodide in N,N-dimethyl-formamide T=100°C; 6 h;
参考文献
L'abbe, Gerrit; Leurs, Stefan; Sannen, Ingrid; Dehaen, Wim
Tetrahedron, 1993 , vol. 49, # 20 p. 4439 - 4446
反应条件
sodium iodide in N,N-dimethyl-formamide T=100°C;
参考文献
Journal of the American Chemical Society, , vol. 118, # 39 p. 9295 - 9306
反应条件
potassium carbonate in methanol; dichloromethane
参考文献
European Journal of Medicinal Chemistry, , vol. 76, p. 369 - 375
反应条件
1: With hydrogen fluoride T=0°C; 5 h; 2: With sodium carbonate cooling; Further stages.;
参考文献
Journal of Organic Chemistry, , vol. 73, # 7 p. 2875 - 2878
反应条件
1.1: hydrazine / ethanol; water / 24 h / 20 °C 1.2: 0.5 h / 20 °C / pH 3 1.3: 0.25 h / 20 °C 2.1: triethylamine / dichloromethane / 20 °C / Ice/water bath View Scheme
反应条件
hydrazine hydrate in ethanol T=20°C; 1 h;
参考文献
CUBIST PHARMACEUTICALS, INC.; GU, Yu Gui; HE, Yong; YIN, Ning; ALEXANDER, Dylan, C.; CROSS, Jason, B.; METCALF, Chester, A., III.; BUSCH, Robert
Patent: WO2013/149136 A1, 2013 ;
Location in patent: Page/Page column 70; 71 ;
反应条件
1: triethylamine; palladium diacetate; triphenylphosphine; copper(l) iodide / 20 °C / |Inert atmosphere 2: N-iodo-succinimide; trimethylsilylazide / 1,2-dichloro-ethane; acetonitrile / 3 h / 20 - 70 °C View Scheme
参考文献
Okamoto, Noriko; Ishikura, Minoru; Yanada, Reiko
Organic Letters, 2013 , vol. 15, # 11 p. 2571 - 2573
反应条件
1: triethylamine; palladium diacetate; triphenylphosphine; copper(l) iodide / 20 °C / |Inert atmosphere 2: N-iodo-succinimide; trimethylsilylazide / 1,2-dichloro-ethane; acetonitrile / 3 h / 20 - 70 °C View Scheme
参考文献
Okamoto, Noriko; Ishikura, Minoru; Yanada, Reiko
Organic Letters, 2013 , vol. 15, # 11 p. 2571 - 2573
