1-氯-4-(2-硝基乙基)苯合成路线 （共 8 条）
反应条件
sodium hydroxide; sulfuric acid 1.) ethanol, room temperature, 5 min, 2.) n-pentane, 0 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Chikashita, H.; Morita, Y.; Itoh, K.
Synthetic Communications, 1987 , vol. 17, # 6 p. 677 - 684
反应条件
samarium diiodide; water; isopropylamine in tetrahydrofuran
参考文献
Tetrahedron Letters, , vol. 48, # 32 p. 5707 - 5710
反应条件
formic acid; [(η5-C5Me5)2Rh2(μ-Cl)2Cl2]; triethylamine; N-(2-amino-ethyl)-4-methyl-benzenesulphonamide in ethyl acetate
T=28°C; 2 h; chemoselective reaction;
参考文献
Xiang, Jing; Sun, Er-Xiao; Lian, Chun-Xia; Yuan, Wei-Cheng; Zhu, Jin; Wang, Qiwei; Deng, Jingen
Tetrahedron, 2012 , vol. 68, # 24 p. 4609 - 4620
反应条件
PBI in butan-1-ol
1 h; Heating;
参考文献
Chikashita, Hidenori; Nishida, Shuichi; Miyazaki, Makoto; Morita, Yasuhiro; Itoh, Kazuyoshi
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 2 p. 737 - 746
参考文献
Itoh, Kazuyoshi; Ishida, Hideaki; Chikashita, Hidenori
Chemistry Letters, 1982 , p. 1117 - 1118
反应条件
1: cyclohexylamine; acetic acid / 6 h / Reflux
2: sodium tetrahydroborate; silica gel / dichloromethane; isopropyl alcohol / 0.33 h / 20 °C
View Scheme
参考文献
McNamara, Yvonne M.; Cloonan, Suzanne M.; Knox, Andrew J.S.; Keating, John J.; Butler, Stephen G.; Peters, Guenther H.; Meegan, Mary J.; Williams, D. Clive
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 3 p. 1328 - 1348
反应条件
(i) NaOEt, EtOH, (ii) /BRN= 4226140/, DMSO; Multistep reaction;
参考文献
Katritzky,A.R. et al.
Journal of the Chemical Society, Chemical Communications, 1979 , p. 602
反应条件
(i) Et3N, (ii) H2SO4, (iii) NaBH4, Ac2O, DMSO; Multistep reaction;
参考文献
Seebach,D. et al.
Chemische Berichte, 1979 , vol. 112, p. 234 - 248
