反式-1,2-二羟基-1,2-二氢菲合成路线 （共 6 条）
反应条件
1: n-BuLi / tetrahydrofuran / 4 h / -78 - 20 °C
2: H2 / PtO2 / benzene; ethanol / 4 h / Ambient temperature
3: BF3*Et2O, EtSH / CH2Cl2 / 6 h / 0 °C
4: 98 percent
5: 75 percent / BBr3 / -20 °C
6: Cr(ClO4)2, ethylenediamine / dimethylformamide / 0.33 h / 0 °C
View Scheme
参考文献
Koreeda, Masato; Jung, Kee-Yong; Hirota, Mitsuru
Journal of the American Chemical Society, 1990 , vol. 112, # 20 p. 7413 - 7414
反应条件
1: 75 percent / BBr3 / -20 °C
2: Cr(ClO4)2, ethylenediamine / dimethylformamide / 0.33 h / 0 °C
View Scheme
参考文献
Koreeda, Masato; Jung, Kee-Yong; Hirota, Mitsuru
Journal of the American Chemical Society, 1990 , vol. 112, # 20 p. 7413 - 7414
参考文献
Lehr,R.E. et al.
Journal of Organic Chemistry, 1977 , vol. 42, # 4 p. 736 - 744
反应条件
1: 1.) NaH; 2.) phenylseleninic anhydride
2: 46 percent / LiAlH4 / diethyl ether / 2 h
View Scheme
参考文献
Sukumaran, K.B.; Harvey, Ronald G.
Journal of Organic Chemistry, 1980 , vol. 45, # 22 p. 4407 - 4413
反应条件
1: I2
2: NBS, AIBN
3: NaHCO3
4: NH3 / methanol
View Scheme
参考文献
Lehr,R.E. et al.
Journal of Organic Chemistry, 1977 , vol. 42, # 4 p. 736 - 744
反应条件
1: NBS, AIBN
2: NaHCO3
3: NH3 / methanol
View Scheme
参考文献
Lehr,R.E. et al.
Journal of Organic Chemistry, 1977 , vol. 42, # 4 p. 736 - 744
