1-苄基-1,2,4-噻唑合成路线 （共 19 条）
反应条件
potassium tert-butylate in N,N-dimethyl-formamide T=75°C; 0.5 h;
参考文献
Paventi, Martino; Elce, Edmund; Jackman, Rebecca J.; Hay, Allan S.
Tetrahedron Letters, 1992 , vol. 33, # 43 p. 6405 - 6406
反应条件
potassium carbonate; potassium iodide in acetone
Inert atmosphereReflux;
参考文献
Doiron, Jeremie; Soultan, Al Haliffa; Richard, Ryan; Toure, Mamadou Mansour; Picot, Nadia; Richard, Remi; Cuperlovic-Culf, Miroslava; Robichaud, Gilles A.; Touaibia, Mohamed
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4010 - 4024
反应条件
T=165°C; 0.0833333 h; microwave irradiation;
参考文献
Abenhaim, David; Diez-Barra, Enrique; Hoz, Antonio de la; Loupy, Andre; Sanchez-Migallon, Ana
Heterocycles, 1994 , vol. 38, # 4 p. 793 - 802
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
T=0 - 20°C; Alkylation;
参考文献
Bulger, Paul G.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf-H.
Tetrahedron Letters, 2000 , vol. 41, # 8 p. 1297 - 1301
反应条件
hydrogenchloride; sodium nitrite
T=0 - 20°C;
参考文献
Astleford, Bret A.; Goe, Gerald L.; Keay, James G.; Scriven, Eric F. V.
Journal of Organic Chemistry, 1989 , vol. 54, # 3 p. 731 - 732
参考文献
Gasparini, J. P.; Gassend, R.; Maire, J. C.; Elguero, J.
Journal of Organometallic Chemistry, 1980 , vol. 188, # 2 p. 141 - 150
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
T=20°C; 24 h; Inert atmosphere;
参考文献
Zink, Daniel M.; Volz, Daniel; Baumann, Thomas; Mydlak, Mathias; Fluegge, Harald; Friedrichs, Jana; Nieger, Martin; Braese, Stefan
Chemistry of Materials, 2013 , vol. 25, # 22 p. 4471 - 4486
反应条件
nanosized zeolite Beta; air
T=135°C; 48 h; Green chemistry;
参考文献
Reddy, Marri Mahender; Kumar, Macharla Arun; Swamy, Peraka; Naresh, Mameda; Srujana, Kodumuri; Satyanarayana, Lanka; Venugopal, Akula; Narender, Nama
Green Chemistry, 2013 , vol. 15, # 12 p. 3474 - 3483
反应条件
benzyl bromide
T=180°C; 5 h;
参考文献
Smith, Keith; Small, Andrew; Hutchings, Michael G.
Chemistry Letters, 1990 , # 3 p. 347 - 350
反应条件
sodium hydroxide in N,N-dimethyl-formamide
2 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Katritzky, Alan R.; Kuzmierkiewiecz, Wojciech; Greenhill, John V.
Recueil des Travaux Chimiques des Pays-Bas, 1991 , vol. 110, # 9 p. 369 - 373
