(S)-3-氯-1,2-丙二醇合成路线 （共 25 条）
反应条件
potassium dioxotetrahydroxoosmate(VI); potassium carbonate; potassium hexacyanoferrate(III); 1,4-bis(dihydroquinidinyl)anthraquinone in water; tert-butyl alcohol T=0°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Angewandte Chemie, , vol. 108, # 4 p. 447 - 449
反应条件
sodium hydroxide; PEP; adenosine 5'-triphosphoric acid; 2-hydroxyethanethiol; magnesium chloride in water T=27°C; 120 h; pH=7.5; Yield given. Yields of byproduct given;
参考文献
Journal of the American Chemical Society, , vol. 107, # 24 p. 7019 - 7027
反应条件
polistyrene-bound (R,R)-N-(3,5-di-t-butyl-6-hydroxy)benzylidene-N'-(3-t-butyl-2,5-dihydroxy)benzylidene-1,2-cyclohexanediamine; water in dichloromethane 3 h; Ambient temperature; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 121, # 17 p. 4147 - 4154
反应条件
epoxide hydrolase from Agrobacterium radiobacter AD1; halohydrin dehalogenase from Agrobacterium radiobacter AD1; Tris-SO4 buffer in water T=30°C; kinetic resolution; pH=7.5; 20 h; Further byproducts given;
参考文献
Lutje Spelberg, Jeffrey H.; Van Hylckama Vlieg, Johan E. T.; Bosma, Tjibbe; Kellogg, Richard M.; Janssen, Dick B.
Tetrahedron Asymmetry, 1999 , vol. 10, # 15 p. 2863 - 2870
反应条件
water; poly(Co(III)(OTs)-salen-norbornene) in chlorobenzene T=20°C; 0.5 h; Product distribution; Further Variations:Catalystsreaction times;
参考文献
Journal of Organic Chemistry, , vol. 71, # 5 p. 1825 - 1836
反应条件
sodium methylate in methanol 4 h; Ambient temperature;
参考文献
Tetrahedron: Asymmetry, , vol. 4, # 10 p. 2211 - 2218
反应条件
sodium hydroxide; sodium azide; acid phosphatase; pyruvate kinase; Phosphoenolpyruvate; glycerol kinase from Streptomyces canus; potassium chloride; adenosine 5'-triphosphoric acid; 2-hydroxyethanethiol; magnesium chloride 1.) H2O, 25 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 63, # 12 p. 4039 - 4045
反应条件
porcine pancreatic lipase; sodium methylate 1) H2O (pH:7), r.t., 2) MeOH, r.t., 4h; Multistep reaction;
参考文献
Tetrahedron: Asymmetry, , vol. 4, # 10 p. 2211 - 2218
反应条件
sulfuric acid 1 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Agricultural and Biological Chemistry, , vol. 46, # 5 p. 1153 - 1157
参考文献
Tetrahedron Asymmetry, , vol. 5, # 2 p. 239 - 246
