(S)-3-氯-1,2-丙二醇合成路线 （共 25 条）
反应条件
(S,S)-salen-Co(III)-OAc complex; H2O (dist.) T=0°C; 14 h;
参考文献
Tetrahedron Letters, , vol. 48, # 22 p. 3793 - 3796
反应条件
Serratia-derived glycerol dehydrogenase; Reduced nicotinamide-adenine dinucleotide T=30°C; pH=6.5; 2 h; Aqueous phophate bufferEnzymatic reaction;
参考文献
EP1422213 A1, ;
Page 18 ;
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; water in tetrahydrofuran T=0 - 20°C;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
potassium dihydrogenphosphate; D-glucose in water T=30°C; pH=5.5; 24 h; Aqueous phophate bufferMicrobiological reaction;
参考文献
EP1422213 A1, ;
Page 13 ;
反应条件
water; dimeric chiral (salen)Co complex linked with Al T=20°C; 5 h; Product distribution; Further Variations:Catalysts;
参考文献
Berkessel, Albrecht; Ertuerk, Erkan
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 18 p. 2619 - 2625
反应条件
1: With N,N'-bis(3,5-di-tert-butylsalicylidene)ethylenediaminocobalt(II); camphor-10-sulfonic acid; oxygen in tetrahydrofuran 1 h; 2: (S)-(+)-epichlorohydrin With water in tetrahydrofuran T=20°C; 20 h;
参考文献
Yaegashi, Keisuke; Furukawa, Yoshiro
Patent: US2004/24254 A1, 2004 ;
Location in patent: Page 4 ;
反应条件
1: epichlorohydrin With water; (S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc in tetrahydrofuran T=0°C; 3 h; 2: BocNHSES in tetrahydrofuran T=0°C; 3 h;
参考文献
Angewandte Chemie - International Edition, , vol. 43, # 30 p. 3952 - 3954
反应条件
1: epichlorohydrin With water; (S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc in tetrahydrofuran T=0 - 20°C; 24 h; 2: N-Boc-2-nitrobenzenesulfonamide in tetrahydrofuran T=20°C; 24 h;
参考文献
Angewandte Chemie - International Edition, , vol. 43, # 30 p. 3952 - 3954
反应条件
in Na4e(CN)610H2; water; ethyl acetate; toluene
参考文献
SEPRACOR, INC.
Patent: EP643781 B1, 1998 ;
参考文献
Rhodia ChiRex, Inc.
Patent: US2003/73855 A1, 2003 ;
