8-甲氧基-1,2-二氢-萘合成路线 （共 12 条）
反应条件
1: 78 percent / N-methylmorpholine N-oxide, osmium tetroxide / H2O; acetone; 2-methyl-propan-2-ol; CCl4 2: 97 percent / p-toluenesulfonic acid / benzene / 0.25 h / Heating View Scheme
参考文献
Hauser, Frank M.; Prasanna, Subbarao
Synthesis, 1980 , # 8 p. 621 - 623
反应条件
2-chloro-2,5-cyclohexadiene-1,4-dione in 1,4-dioxane T=40°C; also with DDQ; Rate constantMechanism;
参考文献
Radtke, Rainer; Hintze, Horst; Roesler, Klaus; Heesing, Albert
Chemische Berichte, 1990 , vol. 123, p. 627 - 634
反应条件
toluene-4-sulfonic acid in benzene
T=70°C; 6 h;
参考文献
Penick, Mark A.; Mahindaratne, Mathew P. D.; Gutierrez, Robert D.; Smith, Terrill D.; Tiekink, Edward R. T.; Negrete, George R.
Journal of Organic Chemistry, 2008 , vol. 73, # 16 p. 6378 - 6381
反应条件
toluene-4-sulfonic acid; 3-hydroxy-2,2-dimethylpropanol in toluene
48 h; Reflux;
参考文献
Imai, Masao; Morais, Goreti Ribeiro; Al-Hindawi, Bassam; Al-Sulaibi, Mazen A.M.; Meetani, Mohammad; Thiemann, Thies
Journal of Chemical Research, 2010 , # 6 p. 325 - 329
反应条件
isopropylmagnesium chloride; bis(1,5-cyclooctadiene)nickel (0) in tetrahydrofuran; toluene
T=55°C; 1 h;
参考文献
Busacca, Carl A.; Eriksson, Magnus C.; Fiaschi, Rita
Tetrahedron Letters, 1999 , vol. 40, # 16 p. 3101 - 3104
反应条件
toluene-4-sulfonic acid; ethylene glycol in toluene
T=80°C; 16 h;
参考文献
Harrowven, David C; Tyte, Melloney J
Tetrahedron Letters, 2002 , vol. 43, # 34 p. 5971 - 5972
反应条件
potassium hydroxide; sodium hydroxide
T=300°C;
参考文献
Eastham; Larkin
Journal of the American Chemical Society, 1958 , vol. 80, p. 2887,2892
反应条件
NiCl2(dppb) in tetrahydrofuran; toluene
T=55°C; 1 h;
参考文献
Busacca, Carl A.; Eriksson, Magnus C.; Fiaschi, Rita
Tetrahedron Letters, 1999 , vol. 40, # 16 p. 3101 - 3104
反应条件
bis(1,5-cyclooctadiene)nickel (0) in tetrahydrofuran; toluene
T=55°C; 1 h;
参考文献
Busacca, Carl A.; Eriksson, Magnus C.; Fiaschi, Rita
Tetrahedron Letters, 1999 , vol. 40, # 16 p. 3101 - 3104
反应条件
thionyl chloride
Title compound not separated from byproducts;
参考文献
Perrone, R; Berardi, F; Tortorella, V; Govoni, S; Lograno, MD; Daniele, E
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 9 p. 869 - 874
