2,3-二甲氧基-6-溴苯甲酸合成路线 （共 15 条）
反应条件
sodium hydroxide; N-bromosuccinmide in water T=0 - 20°C; 48 h;
参考文献
Magnin, David R.; Sulsky, Richard B.; Robl, Jeffrey A.; Caulfield, Thomas J.; Parker, Rex A.
Patent: US2003/225091 A1, 2003 ;
Location in patent: Page column 66 ;
反应条件
sodium hydroxide; silver nitrate in water; acetonitrile T=20°C; 16 h;
参考文献
Bernardo, Paul H.; Wan, Kah-Fei; Sivaraman, Thirunavukkarasu; Xu, Jin; Moore, Felicity K.; Hung, Alvin W.; Mok, Henry Y. K.; Yu, Victor C.; Chai, Christina L. L.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 21 p. 6699 - 6710
反应条件
sodium hydroxide T=20°C;
参考文献
Couty, Sylvain; Meyer, Christophe; Cossy, Janine
Tetrahedron Letters, 2006 , vol. 47, # 5 p. 767 - 769
反应条件
pyridine; 7,8-methylenedioxy-4,5-dihydro-3H-3-benzazepine in benzene T=20°C; 12 h;
参考文献
Journal of Organic Chemistry, , vol. 74, # 15 p. 5486 - 5495
反应条件
1: 96 percent / K2CO3 / dimethylformamide / 5 h / 110 - 120 °C 2: 70 percent / KMnO4 / acetone; H2O / 3 h / 50 - 60 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 47, # 5 p. 951 - 956
反应条件
1: 1.) Br2, KBr, 2.) NaOH / 1.) H2O, 6 h, 2.) H2O, 6 h 2: 96 percent / K2CO3 / dimethylformamide / 5 h / 110 - 120 °C 3: 70 percent / KMnO4 / acetone; H2O / 3 h / 50 - 60 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 47, # 5 p. 951 - 956
反应条件
2: 96.5 percent / BBr3 / CH2Cl2 / 20 °C 3: 76 percent / K2CO3 / dimethylformamide / 0.5 h / 110 °C 4: 77 percent / KMnO4 / pyridine; H2O / 2 h / 20 °C View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 47, # 8 p. 2140 - 2144
反应条件
1: 96.5 percent / BBr3 / CH2Cl2 / 20 °C 2: 76 percent / K2CO3 / dimethylformamide / 0.5 h / 110 °C 3: 77 percent / KMnO4 / pyridine; H2O / 2 h / 20 °C View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 47, # 8 p. 2140 - 2144
反应条件
1: 76 percent / K2CO3 / dimethylformamide / 0.5 h / 110 °C 2: 77 percent / KMnO4 / pyridine; H2O / 2 h / 20 °C View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 47, # 8 p. 2140 - 2144
参考文献
Journal of the Chemical Society, , p. 1621,1623
Yakugaku Zasshi, , vol. 54, p. 295,300
Chem.Abstr., , p. 160
