2-硝基-4-苄氧基-5-甲氧基苯甲酸合成路线 （共 23 条）
反应条件
potassium permanganate in acetone T=30 - 50°C; 2 h;
参考文献
HANMI HOLDINGS CO., LTD.; BAE, In Hwan; BYUN, Eun Young; JU, Hae Kyoung; SONG, Ji Young; JUNG, Seung Hyun; JUN, Mi Ae; KIM, Ho Seok; JUNG, Young Hee; SHIM, Mi Yon; AHN, Young Gil; KIM, Maeng Sup
Patent: WO2012/30160 A2, 2012 ;
Location in patent: Page/Page column 50 ;
反应条件
nitric acid; tin(IV) chloride in dichloromethane T=-25°C; 0.0833333 h;
参考文献
Thurston; Murty; Langley; Jones
Synthesis, 1990 , # 1 p. 81 - 84
反应条件
lithium hydroxide in tetrahydrofuran; methanol; water T=20°C; 12 h;
参考文献
Kamal, Ahmed; Ramesh; Srinivas; Ramulu; Laxman; Rehana, Tasneem; Deepak; Achary; Nagarajaram
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 20 p. 5427 - 5436
反应条件
1: NaOH 2: HNO3; H2SO4 / CH2Cl2 / -25 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 15 p. 1933 - 1935
反应条件
1: 92 percent / K2CO3 / acetone / 24 h / Heating 2: 78 percent / SnCl4; HNO3 / CH2Cl2 / 0.08 h / -78 °C 3: 83 percent / LiOH / tetrahydrofuran; H2O; methanol / 12 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 20 p. 5427 - 5436
反应条件
1: 78 percent / SnCl4; HNO3 / CH2Cl2 / 0.08 h / -78 °C 2: 83 percent / LiOH / tetrahydrofuran; H2O; methanol / 12 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 20 p. 5427 - 5436
反应条件
1: 92 percent / K2CO3 / acetone / 24 h / Heating 2: 78 percent / SnCl4; HNO3 / CH2Cl2 / 0.08 h / -78 °C 3: 83 percent / LiOH / tetrahydrofuran; H2O; methanol / 12 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 20 p. 5427 - 5436
反应条件
1: NaOH 2: HNO3; H2SO4 / CH2Cl2 / -25 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 15 p. 1933 - 1935
反应条件
1: Ag2O 2: HNO2 View Scheme
参考文献
Heterocycles, , vol. 22, # 2 p. 253 - 256
反应条件
2: Ag2O 3: HNO2 View Scheme
参考文献
Heterocycles, , vol. 22, # 2 p. 253 - 256
