5,6-二氢吡啶-2(1H)-酮合成路线 （共 8 条）
反应条件
Grubb's 2nd generation catalyst in dichloromethane Grubbs Olefin Metathesis; 6 h; Reflux;
参考文献
Rao, Vidadala Ramasubba; Muthenna, Puppala; Shankaraiah, Gundeti; Akileshwari, Chandrasekhar; Babu, Kothapalli Hari; Suresh, Ganji; Babu, Katragadda Suresh; Chandra Kumar, Rotte Sateesh; Prasad, Kothakonda Rajendra; Yadav, Potharaju Ashok; Petrash, J. Mark; Reddy, Geereddy Bhanuprakash; Rao, Janaswamy Madhusudana
European Journal of Medicinal Chemistry, 2012 , vol. 57, p. 344 - 361
反应条件
1: With sodium hydrogencarbonate in dichloromethane 0.166667 h; 2: With 3-chloro-benzenecarboperoxoic acid 1 h; Further stages.;
参考文献
Fincher; Dyer; Dodson; Richards; Tobler; Searcy; Mather; Reid; Rolig; Pidcock
Journal of Chemical Ecology, 2008 , vol. 34, # 4 p. 558 - 574
反应条件
trifluoroacetic acid in dichloromethane T=20°C; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 75, # 8 p. 2610 - 2618
反应条件
1: LDA / tetrahydrofuran; hexane / 1.) -50 deg C, 45 min, 2.) -78 deg C, 7 h 2: 50percent H2O2 / tetrahydrofuran / 1.) 0 deg C, 30 min, 2.) 25 deg C, 1.5 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 17 p. 5084 - 5087
反应条件
1: 78 percent / conc.HCl / ethanol / 6 h / Heating 2: m-CPBA, aq.NaHCO3 / CH2Cl2 / 1 h / 0 °C 3: 1.17 g / benzene / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 21 p. 5741 - 5747
反应条件
ammonia Yield given. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 40, # 1 p. 171 - 176
反应条件
1: 5,6-dihydropyridine-2(1H)-one With n-butyllithium in tetrahydrofuran T=-78°C; 0.75 h; Inert atmosphere; 2: C17H22O6 in tetrahydrofuran T=-78°C; 1 h;
参考文献
Rao, Vidadala Ramasubba; Muthenna, Puppala; Shankaraiah, Gundeti; Akileshwari, Chandrasekhar; Babu, Kothapalli Hari; Suresh, Ganji; Babu, Katragadda Suresh; Chandra Kumar, Rotte Sateesh; Prasad, Kothakonda Rajendra; Yadav, Potharaju Ashok; Petrash, J. Mark; Reddy, Geereddy Bhanuprakash; Rao, Janaswamy Madhusudana
European Journal of Medicinal Chemistry, 2012 , vol. 57, p. 344 - 361
反应条件
in pyridine; toluene T=45°C; 168 h;
参考文献
Boll, Per M.; Hansen, Jesper; Simonsen, Ole; Thorup, Niels
Tetrahedron, 1984 , vol. 40, # 1 p. 171 - 176
