2,3-二甲氧基-5-甲基-1,4-苯醌合成路线 （共 103 条）
反应条件
pyridine-2,6-dicarboxylic acid; ammonium cerium(IV) nitrate in water; acetonitrile
参考文献
Kozhukhova, A. I.; Filippova, T. M.; Obol'nikova, E. A.; Samokhvalov, G. I.; Margulis, M. A.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 3.2 p. 533 - 535
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 3 p. 619 - 621
反应条件
1: Br2 / Fe / CH2Cl2 2: 0.83 g / 2,6-pyridinedicarboxylic acid; ammonium cerium(IV) nitrate / H2O; acetonitrile / 20 °C 3: 100 percent / CH2Cl2 / 40 h 4: NaOMe / toluene / 2 h / 0 - 20 °C 5: 96 percent / maleic anhydride / toluene / 4 h / Heating View Scheme
参考文献
European Journal of Organic Chemistry, , # 1 p. 189 - 202
反应条件
1: MnO2 / diethyl ether; H2O 2: Br2 / Fe / CH2Cl2 3: 0.83 g / 2,6-pyridinedicarboxylic acid; ammonium cerium(IV) nitrate / H2O; acetonitrile / 20 °C 4: 100 percent / CH2Cl2 / 40 h 5: NaOMe / toluene / 2 h / 0 - 20 °C 6: 96 percent / maleic anhydride / toluene / 4 h / Heating View Scheme
参考文献
European Journal of Organic Chemistry, , # 1 p. 189 - 202
反应条件
1: boric acid, acetic acid, methyl borate, H2 / 10percent Pd-C / 4 h / 190 °C / 45600 Torr 2: 95.7 percent / ferric chloride*6 H2O / benzene; H2O / 3 h / Ambient temperature View Scheme
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 28, # 5 p. 1648 - 1650
反应条件
1: 1.) ClCO2Et, Et3N, 2.) NaBH4 / 1.) THF, 0-5 deg C, 45 min, 2.) THF, water, room temp., 3 h 2: 95.7 percent / ferric chloride*6 H2O / benzene; H2O / 3 h / Ambient temperature View Scheme
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 28, # 5 p. 1648 - 1650
反应条件
1: 38.7 percent / NaBH4 / dimethylsulfoxide / 3 h / 100 - 110 °C 2: 95.7 percent / ferric chloride*6 H2O / benzene; H2O / 3 h / Ambient temperature View Scheme
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 28, # 5 p. 1648 - 1650
反应条件
1: HCl 2: LiAlH4 / tetrahydrofuran 3: H2 / Pd-C / acetic acid / 2206.5 Torr / Ambient temperature 4: aq. H2O2, AcOH View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 763, p. 109 - 120
反应条件
potassium carbonate; silver(l) oxide in benzene 0.166667 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 61, # 26 p. 9168 - 9177
反应条件
1: NaBr; oxone / acetone; H2O 2: K2CO3 / acetone / 45 °C 3: 100 percent / MCPA; p-TsOH / CHCl3 / 3 h / 50 °C 4: Na / methanol / 20 °C 5: CuBr / dimethylformamide; H2O / 130 °C 6: O2 / Co(salen) View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 8 p. 1255 - 1257
反应条件
1: K2CO3 / acetone / 45 °C 2: 100 percent / MCPA; p-TsOH / CHCl3 / 3 h / 50 °C 3: Na / methanol / 20 °C 4: CuBr / dimethylformamide; H2O / 130 °C 5: O2 / Co(salen) View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 8 p. 1255 - 1257
