1-β-D-阿拉伯呋喃糖苷胸腺嘧啶合成路线 （共 17 条）
反应条件
carbonic acid diphenyl ester; copper; sodium hydrogencarbonate in N,N-dimethyl-formamide T=140 - 150°C; 45 h;
参考文献
Cech, D.; Schwarz, B.; Pein, C. D.
Journal fuer Praktische Chemie (Leipzig), 1983 , vol. 325, # 3 p. 387 - 392
反应条件
nickel in ethanol Heating;
参考文献
Reese, Colin B.; Sanghvi, Yogesh S.
Journal of the Chemical Society, Chemical Communications, 1983 , # 16 p. 877 - 879
反应条件
ammonium hydroxide T=70°C; 14 h;
参考文献
Sawai, Hiroaki; Hayashi, Hidekazu; Sekiguchi, Sumie
Chemistry Letters, 1994 , # 3 p. 605 - 606
反应条件
1: 96 percent 2: 95 percent / N,N-dimethyl-acetamide / Ambient temperature 3: 32 percent / potassium tert-butoxide / 2-methyl-propan-2-ol / 20 h / 25 °C 4: 100 percent / aq. ammonia / 14 h / 70 °C View Scheme
参考文献
Chemistry Letters, , # 3 p. 605 - 606
反应条件
1: 95 percent / N,N-dimethyl-acetamide / Ambient temperature 2: 32 percent / potassium tert-butoxide / 2-methyl-propan-2-ol / 20 h / 25 °C 3: 100 percent / aq. ammonia / 14 h / 70 °C View Scheme
参考文献
Chemistry Letters, , # 3 p. 605 - 606
反应条件
1: 45 percent / BM-11 E. coli cells, 0.015 M potassium phosphate buffer (pH 7.25); 1.) 60 deg C, 2 h, 2.) 4 deg C, 18 h 2: 1.) acetylsalicylic chloroanhydride, 2.) 0.5 N HCl / 1.) nitromethane, 20 deg C, 15 h, 2.) water, dioxane, 100 deg C, 2.5 h View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 23, # 6 p. 493 - 496
Khimiko-Farmatsevticheskii Zhurnal, , vol. 23, # 6 p. 699 - 702
反应条件
1: H2O / 0.25 h / Heating 2: ethanol / 0.25 h / Heating 3: 66 percent / Raney-Ni / ethanol / Heating View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 16 p. 877 - 879
反应条件
1: ethanol / 0.25 h / Heating 2: 66 percent / Raney-Ni / ethanol / Heating View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 16 p. 877 - 879
反应条件
1: 93 percent / SnCl4 / 1,2-dichloro-ethane / 48 h / 20 °C 2: 80 percent / 1 N sodium methylate / methanol / 3 h / 20 °C 3: 1.) acetylsalicylic chloroanhydride, 2.) 0.5 N HCl / 1.) nitromethane, 20 deg C, 15 h, 2.) water, dioxane, 100 deg C, 2.5 h View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 23, # 6 p. 493 - 496
Khimiko-Farmatsevticheskii Zhurnal, , vol. 23, # 6 p. 699 - 702
反应条件
1: 80 percent / 1 N sodium methylate / methanol / 3 h / 20 °C 2: 1.) acetylsalicylic chloroanhydride, 2.) 0.5 N HCl / 1.) nitromethane, 20 deg C, 15 h, 2.) water, dioxane, 100 deg C, 2.5 h View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 23, # 6 p. 493 - 496
Khimiko-Farmatsevticheskii Zhurnal, , vol. 23, # 6 p. 699 - 702
