3-苯基-2,4(1H,3H)-喹唑啉二酮合成路线 （共 81 条）
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; potassium carbonate in tetrahydrofuran T=70 - 80°C; Addition; carbonylation; cyclization; P=15514.9 Torr; 12 h;
参考文献
Larksarp, Chitchamai; Alper, Howard
Journal of Organic Chemistry, 2000 , vol. 65, # 9 p. 2773 - 2777
反应条件
selenium; triethylamine in tetrahydrofuran T=170°C; P=15001.5 Torr; 11 h;
参考文献
Wu, Xiaowei; Yu, Zhengkun
Tetrahedron Letters, 2010 , vol. 51, # 11 p. 1500 - 1503
反应条件
sodium hydroxide in ethanol
参考文献
Papadopoulos, E. P.; Torres, C. D.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 269 - 272
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane T=0°C; Oxidation; Rearrangement; 0.75 h;
参考文献
Azizian, Javad; Mehrdad, Morteza; Jadidi, Khosrow; Sarrafi, Yaghob
Tetrahedron Letters, 2000 , vol. 41, # 27 p. 5265 - 5268
反应条件
tris(dibenzylideneacetone)dipalladium (0); caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane T=100°C; 48 h;
参考文献
Willis, Michael C.; Snell, Robert H.; Fletcher, Anthony J.; Woodward, Robert L.
Organic Letters, 2006 , vol. 8, # 22 p. 5089 - 5091
参考文献
Takeda Chemical Industries, Inc.
Patent: US6407116 B1, 2002 ;
反应条件
hydrogenchloride in tetrahydrofuran; water T=65°C; 72 h;
参考文献
Mirallai, Styliana I.; Manos, Manolis J.; Koutentis, Panayiotis A.
Journal of Organic Chemistry, 2013 , vol. 78, # 19 p. 9906 - 9913
反应条件
sodium hydride in N,N-dimethyl-formamide; benzene T=80°C; 5 h;
参考文献
Minami, Toru; Ogata, Masanori; Hirao, Ichiro; Tanaka, Masaya; Agawa, Toshio
Synthesis, 1982 , # 3 p. 231 - 233
反应条件
in N,N-dimethyl-formamide T=150°C; 5 h; Sealed vialMicrowave irradiation;
参考文献
Tetrahedron Letters, , vol. 52, # 29 p. 3793 - 3796
反应条件
iodine T=80°C; 0.75 h; Ionic liquid;
参考文献
Wang, Shu-Liang; Yang, Ke; Yao, Chang-Sheng; Wang, Xiang-Shan.
Synthetic Communications, 2012 , vol. 42, # 3 p. 341 - 349
