1,2-二甲基-3,4-二硝基苯合成路线 （共 14 条）
反应条件
nitric acid T=140°C;
参考文献
Momose,T. et al.
Chemical and Pharmaceutical Bulletin, 1964 , vol. 12, p. 14 - 18
反应条件
1: HNO3 / 140 °C 2: D-glucose, aq. Na2CO3 3: D-glucose, aq. Na2CO3 4: (i) NaNO2, aq. HCl, (ii) aq. EtOH View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 12, p. 14 - 18
参考文献
Canadian Journal of Chemistry, , vol. 42, p. 63 - 68
参考文献
Journal of the Chemical Society, , vol. 119, p. 1052
反应条件
sulfuric acid
T=35°C; 18 h;
参考文献
Fischer, Alfred; Henderson, George N.; Iyer, Lokanathan M.
Canadian Journal of Chemistry, 1985 , vol. 63, p. 2390 - 2400
反应条件
nitric acid
T=22 - 25°C; die Isomeren werden durch fraktionierte Krystallisation aus konz. Schwefelsaeure getrennt;
参考文献
Crossley; Renouf
Journal of the Chemical Society, 1909 , vol. 95, p. 208
反应条件
1: 23 percent / methanol
2: 58 percent / boron trifluoride-etherate / 1.2 h / 0 °C
3: 1) nitric acid, acetic anhydride, trifluoroacetic acid / 1) 0 deg C, 5 min, 2) acetic anhydride, 0 deg C, 2 h
View Scheme
参考文献
Fischer, Alfred; Henderson, George N.; Iyer, Lokanathan M.
Canadian Journal of Chemistry, 1985 , vol. 63, p. 2390 - 2400
反应条件
1: 58 percent / boron trifluoride-etherate / 1.2 h / 0 °C
2: 1) nitric acid, acetic anhydride, trifluoroacetic acid / 1) 0 deg C, 5 min, 2) acetic anhydride, 0 deg C, 2 h
View Scheme
参考文献
Fischer, Alfred; Henderson, George N.; Iyer, Lokanathan M.
Canadian Journal of Chemistry, 1985 , vol. 63, p. 2390 - 2400
反应条件
nitric acid; acetic anhydride; trifluoroacetic acid
1) 0 deg C, 5 min, 2) acetic anhydride, 0 deg C, 2 h; Yield given. Multistep reaction. Further byproducts given;
参考文献
Fischer, Alfred; Henderson, George N.; Iyer, Lokanathan M.
Canadian Journal of Chemistry, 1985 , vol. 63, p. 2390 - 2400
反应条件
nitric acid; acetic anhydride; trifluoroacetic acid
1) 0 deg C, 5 min, 2) acetic anhydride, 0 deg C, 2 h; Yield given. Multistep reaction. Further byproducts given;
参考文献
Fischer, Alfred; Henderson, George N.; Iyer, Lokanathan M.
Canadian Journal of Chemistry, 1985 , vol. 63, p. 2390 - 2400
