N-甲基-2'-苯甲酰-2,4'-二氯乙酰苯胺合成路线 （共 7 条）
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; ammonia; nitric acid in methanol; water; toluene
参考文献
Hoffmann-La Roche Inc.
Patent: US3996209 A1, 1976 ;
反应条件
ammonia in ethanol T=80°C; 2 h; Further byproducts given;
参考文献
Clarke, George M.; Lee, J. Barry; Swinbourne, Frederick J.; Williamson, Basil
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4745 - 4761
反应条件
ammonia in ethanol T=80°C; 2 h; further reagent; Mechanism;
参考文献
Clarke, George M.; Lee, J. Barry; Swinbourne, Frederick J.; Williamson, Basil
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4745 - 4761
反应条件
sodium hydrogencarbonate in toluene
T=40°C; 2 h;
参考文献
Clarke, George M.; Lee, J. Barry; Swinbourne, Frederick J.; Williamson, Basil
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4745 - 4761
反应条件
ammonia in ethanol
T=80°C; 2 h; Further byproducts given;
参考文献
Clarke, George M.; Lee, J. Barry; Swinbourne, Frederick J.; Williamson, Basil
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4745 - 4761
反应条件
1: 94 percent
2: 40percent sodium hydroxide / H2O
3: 38 percent / 220 °C / 0.5 Torr
View Scheme
参考文献
Esteve, Marta E.; Gaozza, Carlos H.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1061 - 1063
反应条件
ammonia in ethanol
T=80°C; 2 h; further reagent; Mechanism;
参考文献
Clarke, George M.; Lee, J. Barry; Swinbourne, Frederick J.; Williamson, Basil
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4745 - 4761
