1,1'-联-2-萘酚合成路线 （共 233 条）
反应条件
1: (R)-6,6'-dibromo-BINOL With n-butyllithium in tetrahydrofuran; hexane T=-78 - -70°C; 5 h; Inert atmosphere; 2: carbonic acid dimethyl ester in tetrahydrofuran; hexane T=-78 - -40°C; 1.5 h; Inert atmosphere; 3: With hydrogenchloride in tetrahydrofuran; hexane; water T=20°C; pH=< 1; Cooling with ice;
参考文献
Verga, Daniela; Percivalle, Claudia; Doria, Filippo; Porta, Alessio; Freccero, Mauro
Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 2319 - 2323
反应条件
tert-butylamine in methanol 48 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 59, # 8 p. 2156 - 2163
反应条件
palladium dichloride in methanol T=40°C; Green chemistry; chemoselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 2-3 p. 341 - 347
反应条件
1: 44 percent / Cu / dimethylformamide / 2 h / Heating 2: KOH / aq. ethanol 3: 85 percent / benzene; pyridine / r.t.; ref., 3 h 4: 93 percent / benzene; pyridine / r.t.,; ref., 3 h 5: 80 percent / Cu / dimethylformamide / 2 h / Heating 6: 88 percent / KOH / aq. ethanol View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 61, p. 3249 - 3254
反应条件
triethylamine in water; acetonitrile T=30°C; pH=8; 1.5 h; Inert atmosphereIrradiationaq. buffer;
参考文献
Journal of Organic Chemistry, , vol. 75, # 10 p. 3477 - 3480
反应条件
triethylamine in water; acetonitrile T=30°C; pH=8; 1.5 h; Inert atmosphereIrradiationaq. buffer;
参考文献
Journal of Organic Chemistry, , vol. 75, # 10 p. 3477 - 3480
反应条件
triethylamine in acetonitrile T=30°C; 1 h; Inert atmosphereIrradiation;
参考文献
Journal of Organic Chemistry, , vol. 75, # 10 p. 3477 - 3480
反应条件
benzylamine; copper dichloride in methanol 48 h; Ambient temperature; Yields of byproduct given;
参考文献
Smrcina, Martin; Vyskocil, Stepan; Polivkova, Jana; Polakova, Jana; Kocovsky, Pavel
Collection of Czechoslovak Chemical Communications, 1996 , vol. 61, # 10 p. 1520 - 1524
反应条件
1.1: 25 percent / Cs2CO3 / dimethylformamide / 20 h / 60 °C 2.1: BBr3 / CH2Cl2 / 48 h / -10 - 20 °C 2.2: SOCl2 / 168 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 44, # 9 p. 1741 - 1745
反应条件
1: 93 percent / benzene; pyridine / r.t.,; ref., 3 h 2: 80 percent / Cu / dimethylformamide / 2 h / Heating 3: 88 percent / KOH / aq. ethanol View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 61, p. 3249 - 3254
