3-羟基-2-硝基苯甲酸合成路线 （共 44 条）
反应条件
potassium hydroxide; water 12 h; Heating / reflux;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2007/125405 A2, 2007 ;
Location in patent: Page/Page column 24; 72 ;
WO 2007/125405 A2
反应条件
AlCl3, aluminium chloride; diethyl-sulphide in dichloromethane T=40°C; 48 h; Inert atmosphere;
参考文献
Jabri, Salman Y.; Overman, Larry E.
Journal of the American Chemical Society, 2013 , vol. 135, # 11 p. 4231 - 4234
反应条件
pyridine hydrochloride
参考文献
Chemische Berichte, , vol. 88, p. 1938,1943
反应条件
chromium(VI) oxide; acetic anhydride; acetic acid weiteres Reagens: H2SO4;
参考文献
Journal of the American Chemical Society, , vol. 76, p. 5579,5584
反应条件
1: NaH / tetrahydrofuran; dimethylformamide 2: KMnO4, aq. NaOH 3: Py*HCl / 180 - 190 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 29, p. 2003 - 2021
反应条件
1: (nitration) 2: NaH / tetrahydrofuran; dimethylformamide 3: KMnO4, aq. NaOH 4: Py*HCl / 180 - 190 °C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 29, p. 2003 - 2021
参考文献
Journal of the Chemical Society, , vol. 119, p. 1431
Recueil des Travaux Chimiques des Pays-Bas, , vol. 40, p. 621
反应条件
1: sulfuric acid; silver sulphate; iodine / 48 h / 20 °C / |Darkness 2: AlCl3, aluminium chloride; diethyl-sulphide / dichloromethane / 48 h / 40 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 78, # 17 p. 8766 - 8788
反应条件
1: sulfuric acid; silver sulphate; iodine / 48 h / 20 °C / |Darkness; |Inert atmosphere 2: diethyl-sulphide; AlCl3, aluminium chloride / dichloromethane / 48 h / 40 °C / |Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 11 p. 4231 - 4234
参考文献
Helvetica Chimica Acta, , vol. 34, p. 611,614
