反应条件
1: 1.) soybean lipoxygenase-1, O2, borate biffer / 1.) 1 atm, 0 deg C, 1 h, 2.) Et2O, room temperature, 0.5 h
2: 60 percent / Ac2O, DMAP / diethyl ether / 15 h / Ambient temperature
3: 1.) Co(tdcpp), O2, Et3SiH, 2.) trimethyl phosphite / 1.) i-PrOH, CH2Cl2, 1 atm, 28 deg C, 1 h, 2.) room temperature, 1 h
4: p-TsOH*H2O / benzene / 1 h / Heating
5: 94 percent / 2M NaOH / H2O; methanol / 1 h / Heating
View Scheme
参考文献
Hayashi, Yoshiki; Nishikawa, Yasushi; Mori, Hirotaka; Matsushita, Yoh-ichi; Sugamoto, Kazuhiro; Matsui, Takanao
Bioscience, Biotechnology, and Biochemistry, 1998 , vol. 62, # 9 p. 1771 - 1773
