5-乙炔-2,4(1h,3H-)-嘧啶二酮(9ci)合成路线 （共 6 条）
反应条件
1: With carbon; sodium hydroxide in water Large scale; 2: With acetic acid in water pH=5; Large scale;
参考文献
Cooke, Jason W. B.; Bright, Robert; Coleman, Mark J.; Jenkins, Kevin P.
Organic Process Research and Development, 2001 , vol. 5, # 4 p. 383 - 386
反应条件
trimethylsilyl iodide; sodium iodide in acetonitrile 1) r.t., 30 h, 2) reflux 1 h;
参考文献
Kundu, Nitya G.; Das, Biswajit; Majumdar, Anjali
Synthesis, 1990 , # 3 p. 243 - 245
反应条件
1: 85 percent / CHCl3 / 2 h / Heating 2: 85 percent / aq. NaOH / methanol / 3 h View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 19, # 3 p. 463 - 464
反应条件
1: 87 percent / methanol / 20 h / Heating 2: 1.) t-Butyl lithium / 1.) THF, pentane, -70 deg C, 15 min, 2.) -70 deg C, 2 h 3: 85 percent / CHCl3 / 2 h / Heating 4: 85 percent / aq. NaOH / methanol / 3 h View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 19, # 3 p. 463 - 464
反应条件
thymidine phosphorylase in aq. phosphate buffer T=37°C; pH=6.8; 2 h; Enzymatic reaction;
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 40 p. 6900 - 6905
反应条件
copper(l) iodide; triethylamine in N,N-dimethyl-formamide
T=120°C; 23 h;
参考文献
Janeba, Zlatko; Balzarini, Jan; Andrei, Graciela; Snoeck, Robert; De Clercq, Erik; Robins, Morris J.
Canadian Journal of Chemistry, 2006 , vol. 84, # 4 p. 580 - 586
