2,3,5-三-O-乙酰基-6-氯嘌呤-9-β-D-呋喃核糖苷合成路线 (共 37 条)
反应条件
N,N-dimethyl-aniline; trichlorophosphate T=115°C; 0.116667 h;
参考文献
Buck, Ildiko M.; Reese, Colin B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 11 p. 2937 - 2942
反应条件
tert-Butyl thionitrate; copper dichloride in acetonitrile T=25°C; 24 h;
参考文献
Kim, Yong Hae
Phosphorus, Sulfur and Silicon and the Related Elements, 1993 , vol. 74, # 1-4 p. 249 - 260
反应条件
triethylamine in acetonitrile T=0°C; 6 h; Reflux;
参考文献
Anglin, Justin L.; Deng, Lisheng; Yao, Yuan; Cai, Guobin; Liu, Zhen; Jiang, Hong; Cheng, Gang; Chen, Pinhong; Song, Yongcheng; Dong, Shuo
Journal of Medicinal Chemistry, 2012 , vol. 55, # 18 p. 8066 - 8074,9
反应条件
tin(IV) chloride in acetonitrile T=20°C;
参考文献
Hong, Wei; Dowden, James
Chinese Chemical Letters, 2011 , vol. 22, # 12 p. 1439 - 1442
反应条件
dichloro-acetic acid; sodium nitrite in tetrahydrofuran
参考文献
Francom, Paula; Janeba, Zlatko; Shibuya, Susumu; Robins, Morris J.
Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6788 - 6796
反应条件
copper(l) iodide; diiodomethane; iodine; isopentyl nitrite in tetrahydrofuran 0.75 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252
反应条件
1: 80 percent / pyridne / 12 h / 50 °C 2: 85 percent / N,N-dimethylaniline; phosphorus oxychloride / 0.22 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 4 p. 782 - 793
反应条件
in N-methyl-acetamide; dichloromethane
反应条件
T=125°C; P=35 - 45 Torr; 3 h;
参考文献
Schmidt, Richard R.; Loesch, Gabriele R.; Fischer, Peter
Chemische Berichte, 1980 , vol. 113, # 9 p. 2891 - 2915
反应条件
N,O-bis-(trimethylsilyl)-acetamide; tin(IV) chloride in acetonitrile T=60°C; Vorbruggen nucleosidation reaction; 2 h; Inert atmosphere;
参考文献
Chemistry - A European Journal, , vol. 17, # 23 p. 6369 - 6381