1-甲基-5-氧代吡咯烷-3-羧酸甲酯合成路线 （共 7 条）
反应条件
toluene-4-sulfonic acid in dichloromethane T=50°C; 16 h; Reflux;
参考文献
CLARIANT FINANCE (BVI) LIMITED; Wacker, Andreas; Hess, Joachim; Kupfer, Rainer; Roesch, Alexander
Patent: US2013/217579 A1, 2013 ;
Location in patent: Paragraph 0078 ;
反应条件
in water T=20°C; 16 h;
参考文献
Stanetty, Peter; Turner, Martin; Mihovilovic, Marko D.
Molecules, 2005 , vol. 10, # 2 p. 367 - 375
参考文献
Fishwick, Colin W. G.; Foster, Richard J.; Carr, Robin E.
Tetrahedron Letters, 1995 , vol. 36, # 51 p. 9409 - 9412
反应条件
sodium hydroxide in methanol; water 24 h; Ambient temperature;
参考文献
Zoretic; Barcelos; Jardin; Bhakta
Journal of Organic Chemistry, 1980 , vol. 45, # 5 p. 810 - 814
反应条件
Lawesson's reagent in tetrahydrofuran T=25 - 30°C;
参考文献
Singh, Rakesh K.; Sinha, Neelima; Jain, Sanjay; Salman, Mohammad; Naqvi, Fehmida; Anand, Nitya
Tetrahedron, 2005 , vol. 61, # 37 p. 8868 - 8874
反应条件
1: 78 percent / NaBH4 / ethanol / 1) 7.5 h (addition); 2) 14h room temp.
2: 76 percent / 12 N HCl / CH2Cl2 / 5.5 h / Ambient temperature
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参考文献
Zoretic; Barcelos; Jardin; Bhakta
Journal of Organic Chemistry, 1980 , vol. 45, # 5 p. 810 - 814
反应条件
sodium tetrahydroborate in ethanol
1) 7.5 h (addition); 2) 14h room temp.;
参考文献
Zoretic; Barcelos; Jardin; Bhakta
Journal of Organic Chemistry, 1980 , vol. 45, # 5 p. 810 - 814
