3-(2-硝基苯基)-1H-吡唑合成路线 （共 4 条）
反应条件
1: 2-nitro-benzaldehyde With toluene-4-sulfonic acid hydrazide in acetonitrile T=20°C; 3 h; 2: With sodium hydroxide in water; acetonitrile 0.333333 h; 3: 1-vinyl-imidazole in water; acetonitrile T=50°C; 48 h;
参考文献
Hu, Youhong; Xu, Bin; Liao, Yun; Nawoschik, Kenneth; Liu, Yixin; Sandrasagra, Anthony; Fathi, Reza; Yang, Zhen
Patent: US2006/183751 A1, 2006 ;
Location in patent: Page/Page column 82 ;
反应条件
hydrazine in ethanol Reflux;
参考文献
WO2012/7006 A1, ;
Page/Page column 32; 33 ;
WO 2012/007006 A1
反应条件
1: isobutyramide / 2 h / Reflux 2: hydrazine / ethanol / Reflux View Scheme
参考文献
WO2012/7006 A1, ;
WO 2012/007006 A1
反应条件
palladium in methanol
参考文献
H. LUNDBECK A/S; KEHLER, Jan; RITZEN, Andreas; LANGGAaRD, Morten; NIELSEN, Jacob; FARAH, Mohamed; LETH-PETERSEN, Sebastian; KILBURN, John Paul
Patent: WO2012/7006 A1, 2012 ;
Location in patent: Page/Page column 33 ;
WO 2012/007006 A1
