N-Cbz-L-苯丙氨醛合成路线 （共 29 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 2 h; 2: With hydrogenchloride; water in tetrahydrofuran
参考文献
AVENTIS PHARMACEUTICALS INC.
Patent: US2008/139556 A1, 2008 ;
Location in patent: Page/Page column 18; 46 ;
反应条件
perchloric acid; triphenylphosphine in dichloromethane T=-30°C; electrolysis, 2.8 F of electricity, graphite plates as anode and cathode;
参考文献
Maeda, Hatsuo; Maki, Toshihide; Ohmori, Hidenobu
Tetrahedron Letters, 1992 , vol. 33, # 10 p. 1347 - 1350
反应条件
diisobutylaluminium hydride in toluene T=-78°C;
参考文献
Tsubaki, Kazunori; Kusumoto, Tomokazu; Hayashi, Noriyuki; Tanima, Daisuke; Fuji, Kaoru; Kawabata, Takeo
Tetrahedron Asymmetry, 2005 , vol. 16, # 3 p. 739 - 743
反应条件
2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; bisacetoxybromate(I) resin in dichloromethane T=20°C; 2 h;
参考文献
Bruenjes, Marco; Sourkouni-Argirusi, Georgia; Kirschning, Andreas
Advanced Synthesis and Catalysis, 2003 , vol. 345, # 5 p. 635 - 642
反应条件
triethylsilane; palladium on activated charcoal in acetone T=20°C; 0.166667 h;
参考文献
Miyazaki, Tohru; Han-Ya, Yuki; Tokuyama, Hidetoshi; Fukuyama, Tohru
Synlett, 2004 , # 3 p. 477 - 480
反应条件
triethylsilane; palladium on activated charcoal in acetone T=20°C; 0.666667 h;
参考文献
Miyazaki, Tohru; Han-Ya, Yuki; Tokuyama, Hidetoshi; Fukuyama, Tohru
Synlett, 2004 , # 3 p. 477 - 480
反应条件
1: 87 percent / Et3N / tetrahydrofuran / 18 h / 20 °C 2: 76 percent / ethyldiisopropylamine; SO3/pyridine / CH2Cl2; dimethylsulfoxide / 0.5 h / cooling View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 24 p. 5449 - 5460
反应条件
1: NaHCO3 2: LiBH4 3: NaHCO3; NaOCl; NaBr / TEMPO / ethyl acetate; toluene; H2O / -5 °C View Scheme
参考文献
Heterocycles, , vol. 54, # 2 p. 581 - 584
反应条件
Li(Et3CO)3AlH in tetrahydrofuran T=0°C;
参考文献
Fehrentz, Jean-Alain; Pothion, Catherine; Califano, Jean-Christophe; Loffet, Albert; Martinez, Jean
Tetrahedron Letters, 1994 , vol. 35, # 48 p. 9031 - 9034
反应条件
lithium tri-t-butoxyaluminum hydride in tetrahydrofuran T=-75 - -70°C; 0.166667 h;
参考文献
Zlatoidsky, Pavol
Tetrahedron Letters, 1995 , vol. 36, # 40 p. 7281 - 7284
