2,4-二氯-3-硝基吡啶合成路线 （共 29 条）
反应条件
N-ethyl-N,N-diisopropylamine; trichlorophosphate
参考文献
Aventis Pharmaceuticals Products Inc.
Patent: US6307054 B1, 2001 ;
反应条件
1: With lithium chloride; trichlorophosphate T=105°C; 2.5 h; Industrial scale; 2: With hydrogenchloride T=105°C; 1 h; Industrial scale;
参考文献
Cleator, Ed; Scott, Jeremy P.; Avalle, Paulo; Bio, Matthew M.; Brewer, Sarah E.; Davies, Antony J.; Gibb, Andrew D.; Sheen, Faye J.; Stewart, Gavin W.; Wallace, Debra J.; Wilson., Robert D.
Organic Process Research and Development, 2013 , vol. 17, # 12 p. 1561 - 1567
反应条件
1: 90 percent / fuming HNO3; conc. H2SO4 / 0.5 h / 0 °C 2: 80 percent / POCl3 / 24 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 22 p. 4288 - 4312
反应条件
1: KNO3; aqueous HNO3 2: water / 140 °C 3: phosphoryl chloride View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 67, p. 29,37
反应条件
1: acetic acid; concentrated aqueous HNO3 2: aqueous NaOH 3: water / 140 °C 4: phosphoryl chloride View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 67, p. 29,37
反应条件
1: water / 140 °C 2: phosphoryl chloride View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 67, p. 29,37
反应条件
1: aqueous NaOH 2: water / 140 °C 3: phosphoryl chloride View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 67, p. 29,37
反应条件
trichlorophosphate Behandeln des Reaktionsgemisches mit Eis;
参考文献
Journal of the Chemical Society, , p. 4985,4990
反应条件
triethylamine in N,N-dimethyl-formamide T=65°C; 2.5 h;
参考文献
Cai, Xiong; Qian, Changgeng
Patent: US2010/184801 A1, 2010 ;
反应条件
ammonia in water T=91°C; P=3067.81 Torr; 7 h; Industrial scale;
参考文献
Cleator, Ed; Scott, Jeremy P.; Avalle, Paulo; Bio, Matthew M.; Brewer, Sarah E.; Davies, Antony J.; Gibb, Andrew D.; Sheen, Faye J.; Stewart, Gavin W.; Wallace, Debra J.; Wilson., Robert D.
Organic Process Research and Development, 2013 , vol. 17, # 12 p. 1561 - 1567
