4-羟基喹啉-2-甲酸甲酯合成路线 （共 7 条）
反应条件
in various solvent(s) T=235 - 240°C; 5 h;
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4439 - 4445
反应条件
sodium methylate in methanol 40 h; Reflux;
参考文献
Guillou, Sandrine; Janin, Yves L.
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1377 - 1384
反应条件
in diphenylether T=240°C; 0.166667 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 2 p. 406 - 409
反应条件
1: methanol / 2 h / Heating 2: various solvent(s) / 5 h / 235 - 240 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4439 - 4445
反应条件
1: methanol / 2 h / Heating 2: diphenyl ether; various solvent(s) / 0.17 h / 240 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 2 p. 406 - 409
反应条件
1: 1.) NaH / 1.) DMF, RT, 0.5 h, 2.) DMF, RT, overnight 2: 70 percent / aq. LiOH / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Zhou, Yuyang; Li, Wanfei; Liu, Yang; Zeng, Liqiang; Su, Wenming; Zhou, Ming
Dalton Transactions, 2012 , vol. 41, # 31 p. 9373 - 9381
反应条件
1: K2CO3 / dimethylformamide / 4 h / Heating
2: 220 mg / NaOH / H2O; methanol / 2 h / 20 °C
View Scheme
参考文献
Manfredini, Stefano; Vertuani, Silvia; Pavan, Barbara; Vitali, Federica; Scaglianti, Martina; Bortolotti, Fabrizio; Biondi, Carla; Scatturin, Angelo; Prasad, Puttur; Dalpiaz, Alessandro
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 20 p. 5453 - 5463
