5'-O-三苯甲基-2',3'-去氢胸苷合成路线 （共 25 条）
反应条件
lithium telluride in tetrahydrofuran 48 h; Ambient temperature;
参考文献
Clive, Derrick L. J.; Wickens, Philip L.; Sgarbi, Paulo W. M.
Journal of Organic Chemistry, 1996 , vol. 61, # 21 p. 7426 - 7437
反应条件
bis(tricyclohexylphosphine)benzylidene ruthenium(IV) dichloride in dichloromethane T=35°C;
参考文献
Ewing; Glacon; Mackenzie; Postel; Len
Tetrahedron, 2003 , vol. 59, # 7 p. 941 - 945
反应条件
dihydrogen peroxide; acetic acid in tetrahydrofuran 1) 0 deg C, 0.25 h, 2) warm to RT over 1 h;
参考文献
Cosford; Schinazi
Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 2161 - 2165
反应条件
methylamine in acetonitrile T=120°C; 18 h;
参考文献
Nucleosides and Nucleotides, , vol. 12, # 9 p. 951 - 966
反应条件
1: aq. NaIO4 / ethanol / 2 h / 20 °C 2: 50 percent / t-BuOK / tetrahydrofuran; toluene / 1 h 3: 79 percent / benzylidene-bis(tricyclohexylphosphine)-dichlororuthenium / CH2Cl2 / 35 °C View Scheme
参考文献
Tetrahedron, , vol. 59, # 7 p. 941 - 945
反应条件
1: 1) LiAlH4 / 1) THF, 0 deg C, warm to RT over 0.25 h, 2) THF, reflux, 3 h; Na, THF, HMPA also used 2: 61 percent / glacial acetic acid, H2O2 / tetrahydrofuran / 1) 0 deg C, 0.25 h, 2) warm to RT over 1 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 6 p. 2161 - 2165
反应条件
in acetonitrile T=120°C; 18 h;
参考文献
Celewicz; Urjasz; Golankiewicz
Nucleosides and Nucleotides, 1993 , vol. 12, # 9 p. 951 - 966
反应条件
in acetonitrile T=120°C; 18 h;
参考文献
Celewicz; Urjasz; Golankiewicz
Nucleosides and Nucleotides, 1993 , vol. 12, # 9 p. 951 - 966
反应条件
in acetonitrile T=120°C; 18 h;
参考文献
Celewicz; Urjasz; Golankiewicz
Nucleosides and Nucleotides, 1993 , vol. 12, # 9 p. 951 - 966
反应条件
1: 60 percent / pyridine / CH2Cl2 / 12 h / 0 - 20 °C 2: aq. NaIO4 / ethanol / 2 h / 20 °C 3: 50 percent / t-BuOK / tetrahydrofuran; toluene / 1 h 4: 79 percent / benzylidene-bis(tricyclohexylphosphine)-dichlororuthenium / CH2Cl2 / 35 °C View Scheme
参考文献
Tetrahedron, , vol. 59, # 7 p. 941 - 945
