(2S,3R)-3-氨基-2-羟基-4-苯丁酸合成路线 （共 35 条）
反应条件
1: 99 percent / potassium carbonate / H2O; dimethylformamide / 5 h / 20 °C 2: 78 percent / BF3*Et2O / 0 - 20 °C 3: hydrochloric acid / H2O; ethanol / 8 h / Heating View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 16, # 18 p. 3124 - 3127
参考文献
Tetrahedron Asymmetry, , vol. 10, # 12 p. 2327 - 2336
反应条件
1: 1N NaOH / diethyl ether; H2O 2: 95 percent / DCC, HOBt, Et3N / CH2Cl2; tetrahydrofuran 3: H2 / Pd black / H2O; methanol View Scheme
参考文献
Kobayashi, Susumu; Isobe, Toshiyuki; Ohno, Masaji
Tetrahedron Letters, 1984 , vol. 25, # 44 p. 5079 - 5082
反应条件
triethylamine in 1,4-dioxane; water; ethyl acetate
参考文献
Nippon Kayaku Kabushiki Kaisha
Patent: US4281180 A1, 1981 ;
反应条件
sodium hydroxide in diethyl ether; water
Yield given;
参考文献
Kobayashi, Susumu; Isobe, Toshiyuki; Ohno, Masaji
Tetrahedron Letters, 1984 , vol. 25, # 44 p. 5079 - 5082
