1-甲硫基-3-甲基丁-3-烯合成路线 （共 7 条）
反应条件
1: 3-methyl-3-butenyl thioacetate With sodium methylate in methanol
T=20°C; 1 h;
2: methyl iodide in methanol
T=20°C; 2 h;
参考文献
Della, Ernest W.; Graney, Sean D.
Organic Letters, 2002 , vol. 4, # 23 p. 4065 - 4067
反应条件
1.1: NaH / dimethylformamide / 1 h / 20 °C
1.2: 90 percent / dimethylformamide / 2 h / 20 °C
2.1: NaOMe / methanol / 1 h / 20 °C
2.2: 75 percent / methanol / 2 h / 20 °C
View Scheme
参考文献
Della, Ernest W.; Graney, Sean D.
Journal of Organic Chemistry, 2004 , vol. 69, # 11 p. 3824 - 3835
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene
T=80°C; 2 h;
参考文献
Della, Ernest W.; Graney, Sean D.
Organic Letters, 2002 , vol. 4, # 23 p. 4065 - 4067
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene
T=80°C; 2 h;
参考文献
Della, Ernest W.; Graney, Sean D.
Organic Letters, 2002 , vol. 4, # 23 p. 4065 - 4067
反应条件
1.1: sodium methoxide / methanol / 1.5 h / 20 °C
1.2: 74 percent / methanol / 2 h / 20 °C
2.1: Bu3SnH; AIBN / benzene / 2 h / 80 °C
View Scheme
参考文献
Della, Ernest W.; Graney, Sean D.
Organic Letters, 2002 , vol. 4, # 23 p. 4065 - 4067
反应条件
1: 57 percent / dicyclohexyldicarbodiimide / CH2Cl2 / 3 h / 0 °C
2: Bu3SnH; AIBN / benzene / 2 h / 80 °C
View Scheme
参考文献
Della, Ernest W.; Graney, Sean D.
Organic Letters, 2002 , vol. 4, # 23 p. 4065 - 4067
反应条件
(i) thiourea, (ii) aq. NaOH, (iii) /BRN= 969135/; Multistep reaction;
参考文献
Cazes,B. et al.
Journal of Organometallic Chemistry, 1979 , vol. 177, p. 67 - 74
